학술논문
Two Patients With Severe COVID Pneumonia Treated With the Seraph-100 Microbind Affinity Blood Filter.
Document Type
Article
Source
Subject
*COVID-19 pandemic
*PNEUMONIA
*CYTOKINES
*INFLAMMATION
*HYPERBARIC oxygenation
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Language
ISSN
0885-0666
Abstract
We present 2 patients with rapidly escalating oxygen requirements from severe acute respiratory syndrome coronavirus 2 infection (COVID-19) treated with the Seraph100 Microbind Affinity Blood Filter under Emergency Use Authorization from the US Federal Drug Administration. The Seraph100 is an extracorporeal hemoperfusion filter previously demonstrated to remove viral particles and pro-inflammatory cytokines from the blood. Treatment with the Seraph100 filter was associated with a rapid improvement in oxygenation and both patients were discharged from the hospital without supplemental oxygen. [ABSTRACT FROM AUTHOR]