부산대학교 도서관

Introduction: Endobronchial ultrasonography‐guided transbronchial biopsy (EBUS‐TBB) with guide sheath (GS) is an effective procedure for diagnosing small peripheral pulmonary lesions (PPLs) (≤20 mm in the largest diameter). However, samples obtained using EBUS‐TBB with GS are small, and the diagnostic yield of small PPLs biopsied using EBUS‐TBB with GS is unsatisfactory. Objectives: The aim of this study was to evaluate the diagnostic yield of small PPLs using EBUS‐TBB without GS compared to that with GS. Materials and Methods: Between 1 April 2013 and 31 March 2015, 276 consecutive lesions were biopsied using EBUS‐TBB with GS or without GS. We retrospectively compared EBUS‐TBB with and without GS in terms of the diagnostic yield and complications related to small PPLs (≤20 mm). Results: Of the 276 lesions who underwent EBUS‐TBB with or without GS, we identified 80 lesions with small PPLs (≤20 mm). Sixty‐two lesions were successfully diagnosed by EBUS‐TBB (77.5%, diagnostic yield). The diagnostic yield of PPLs using EBUS‐TBB without GS was not significantly higher than that using EBUS‐TBB with GS (34/41 = 82.9% and 28/39 = 71.7%, respectively; p = 0.233). However, according to size (≤15 mm or > 15 mm), location (upper, middle/lingular, or lower area), and structure (solid nodule or ground‐glass opacity), the diagnostic yield of small PPLs (≤15 mm) using EBUS‐TBB without GS was significantly higher than with GS (21/26 = 80.7% vs. 8/16 = 50.0%, p = 0.036). There were no complications among the two groups. Conclusions: EBUS‐TBB without GS is an effective and safe procedure for diagnosing small PPLs (≤15 mm) compared to that with GS. [ABSTRACT FROM AUTHOR]