학술논문

COVID-19 Mortality Risk in Down Syndrome: Results From a Cohort Study of 8 Million Adults.
Document Type
Letter
Source
Annals of Internal Medicine. 4/20/2021, Vol. 174 Issue 4, p572-576. 5p. 1 Chart, 1 Graph.
Subject
*COVID-19
*DOWN syndrome
*MEDICAL personnel
*COHORT analysis
Language
ISSN
0003-4819
Abstract
I Objective: i To evaluate Down syndrome as a risk factor for death from COVID-19 through a comprehensive analysis of individual-level data in a cohort study of 8.26 million adults (aged >19 years), as part of a wider COVID-19 risk prediction project commissioned by the U.K. government ([2]). I Discussion: i We estimated a 4-fold increased risk for COVID-19-related hospitalization and a 10-fold increased risk for COVID-19-related death in persons with Down syndrome, a group that is currently not strategically protected. I Background: i At the start of the coronavirus disease 2019 (COVID-19) pandemic, many national health organizations emphasized nonpharmacologic interventions, such as quarantining or physical distancing. [Extracted from the article]