부산대학교 도서관

Foot and mouth disease (FMD) is a contagious viral disease with major economic consequences. Information on the impact of the disease in vaccinated dairy cows kept under intensive management husbandry is poorly characterized. A FMD (virus serotype O\EA-3) outbreak which took place in a large-scale dairy farm in South-West Israel provided an opportunity to evaluate individual cow risk factors, the impact of clinical FMD morbidity on periparturient diseases and on culling. A retrospective cohort study was conducted on all cows and pregnant heifers at late pregnancy on the farm. Mortality among diseased cows was significantly higher in first calf heifers compared to older cows (OR=2.781; P<0.001). Lactating cows were at a higher risk to contract FMD compared to dry cows (OR=2.072; P=0.002). FMD in the dry period was associated with higher clinical metritis and retained fetal membranes incidence (OR=4.765; P=0.015 and OR= 6.951; P=0.001, respectively), but not with ketosis (OR=1.111; P=0.854). The risk of culling of FMD clinically affected cows was significantly higher in comparison to the healthy cows. The risk of culling of FMD affected cows differed between lactating and dry cow in comparison to the healthy cows 6 months after the outbreak (OR=2.698 and OR=4.616; P<0.001 and P=0.002, respectively). The pattern of culling differed between the clinically FMD cases and the healthy cows, as clinically affected cows were culled more hastily (log rank test=0.029) for up to 6 months from the beginning of the outbreak. [ABSTRACT FROM AUTHOR]