학술논문
New tricks for old dogs: unexpected roles for cell cycle regulators revealed using animal models
Document Type
Article
Source
Subject
*CELL cycle
*HOMEOSTASIS
*YEAST
*CELL culture
*PHYSIOLOGICAL control systems
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Language
ISSN
0955-0674
Abstract
Studies in animal models have revealed many surprises regarding the importance of key cell cycle regulators during animal development and homeostasis, underscoring the plasticity and redundancy of cell cycle circuitry within a whole-animal context. Moreover, checkpoint regulators, which are not essential for viability in yeast and cultured cells, play important roles in cell cycle control during development. [Copyright &y& Elsevier]