학술논문
Enterovirus D68 infection among hospitalized children with severe acute respiratory illness in El Salvador and Panama, 2012‐2013.
Document Type
Article
Author
Biggs, Holly M.; Nix, W. Allan; Zhang, Jing; Rogers, Shannon; Clara, Wilfrido; Jara, Jorge H.; Gonzalez, Rosalba; Luciani, Kathia; Brizuela, Yarisa Sujey; Estripeaut, Dora; Castillo, Juan Miguel; De Leon, Tirza; Corro, Mary; Vergara, Ofelina; Rauda, Rafael; Chong, Evens G.; Watson, John T.; Azziz‐Baumgartner, Eduardo; Gerber, Susan I.; Tong, Suxiang
Source
Subject
*HOSPITAL care of children
*ACUTE diseases
*ENTEROVIRUSES
*MIDDLE East respiratory syndrome
*ENTEROVIRUS diseases
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Language
ISSN
1750-2640
Abstract
We assessed EV‐D68 epidemiology and phylogenetics among children aged ≤9 years hospitalized with severe acute respiratory illnesses at five sites in Panama and El Salvador during 2012‐2013. Respiratory specimens positive for enterovirus or rhinovirus were tested by real‐time RT‐PCR for EV‐D68, and partial VP1 gene sequences were determined. Of 715 enrolled children, 17 from sites in both countries were EV‐D68‐positive and commonly had a history of asthma or wheezing. Phylogenetically, 15 of 16 sequences fell into Clade B1, and one into Clade A2. The Central American EV‐D68s were closely related genetically to contemporaneous strains from North America, South America, and the Caribbean. [ABSTRACT FROM AUTHOR]