학술논문
Reference intervals for routine biochemical markers and body mass index: A study based on healthcare center database in northeastern Iran.
Document Type
Article
Author
Ghazizadeh, Hamideh; Yaghooti‐Khorasani, Mahdiyeh; Khodabandeh, Atieh Kamel; Hasanzadeh, Elahe; Sahranavard, Toktam; Banihashem‐Rad, Seyed Hamed; Zare‐Feyzabadi, Reza; Ekhteraee‐Toosi, Mansoureh Sadat; Akbarpour, Ensieh; Timar, Ameneh; Mohammadi‐Bajgiran, Maryam; Assaran‐Darban, Reza; Farkhany, Ehsan Mosa; Oladi, Mohammad Reza; Ferns, Gordon A.; Esmaily, Habibollah; Ghayour‐Mobarhan, Majid
Source
Subject
*BIOMARKERS
*BODY mass index
*ALANINE aminotransferase
*ASPARTATE aminotransferase
*BLOOD lipids
*URIC acid
*YOUNG adults
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Language
ISSN
1521-6543
Abstract
Age‐ and sex‐specific reference intervals (RIs) for some biochemical tests may be useful for their interpretation, due to the variations in lifestyle and genetic, or ethnic factors. The aim of this study was to obtain RIs for some routine biochemical markers including a serum lipid profile, fasting blood glucose (FBG), aspartate and alanine aminotransferase (AST and ALT), uric acid, and body mass index (BMI) in subjects who attended primary healthcare centers. The large database of primary healthcare centers uses RIs to report results for children, adolescents, and young and old adults. RIs were obtained by using the indirect method, recommended by the CLSI Ep28‐A3 guidelines. RIs for FBG, BMI, and serum lipid profile, including triglyceride, total cholesterol, high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol in people aged 18 to 120 years, were obtained without age/sex segmentation. RIs for serum AST, ALT, and uric acid were obtained without age segmentation, though these RIs were higher in males than females. The RIs for AST, ALT, and uric acid were higher in men, while the RIs for the other variables were similar in both sexes. This is the first study reporting the use of indirect RIs for BMI. [ABSTRACT FROM AUTHOR]