학술논문

Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis.
Document Type
Article
Source
Science Advances. 10/28/2020, Vol. 6 Issue 44, p1-15. 15p.
Subject
*BODY temperature
*GOLD ores
*BORON nitride
*RHEUMATOID arthritis
*POISSON'S ratio
*QUANTUM Hall effect
*METHYL methacrylate
*CHEMICAL processes
Language
ISSN
2375-2548
Abstract
The article presents a study that focuses on neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis. It mentions that formation of autoantibodies to carbamylated proteins (anti-CarP) as considered detrimental in the prognosis of erosive rheumatoid arthritis, along with demonstrate that carbamylated proteins present in neutrophil extracellular traps (NETs) enhance pathogenic immune responses and bone destruction.