학술논문

Safety of vaccines administration in hereditary fructose intolerance.
Document Type
Letter
Source
Orphanet Journal of Rare Diseases. 10/1/2020, Vol. 15 Issue 1, p1-7. 7p.
Subject
*VACCINE safety
*FRUCTOSE
*VACCINE refusal
*SYMPTOMS
Language
ISSN
1750-1172
Abstract
Patients with hereditary fructose intolerance need to follow a life-long fructose dietary and drug restriction to prevent symptoms of intoxication. Concerns about vaccines administration have been manifested overtime, for the risk of a life-threatening acute intoxication. For this reason, at Ospedale Pediatrico Bambino Gesù we performed a deepen research from open sources, datasheets and Pharmaceutical Companies informations from the most common Italian and European vaccines, which are carried out in infancy and childhood. As a safe threshold of 2.4 mg/kg/dose was recently established for oral and parenteral (other than i.v.) route, the manuscript clarifies the safe administration of majority of vaccines in patients with hereditary fructose intolerance. [ABSTRACT FROM AUTHOR]