학술논문
Green synthesis of silver nanoparticles from extracts of Pechuel-loeschea leubnitziae: their anti-proliferative activity against the U87 cell line.
Document Type
Article
Author
Source
Subject
*SILVER nanoparticles
*CELL lines
*X-ray photoelectron spectroscopy
*INFRARED spectroscopy
*X-ray spectroscopy
*ULTRAVIOLET-visible spectroscopy
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Language
ISSN
2470-1556
Abstract
The application of green chemistry for the synthesis of nanoparticles is said to be environmentally friendly and cost efficient. The paper reports on the cell anti-proliferative activity of Pechuel-loeschea leubnitziae, synthesis of silver nanoparticles using P. leubnitziae and characterization. The UV–vis spectroscopy confirmed presence of a peak at 400 nm, and Fourier-transform infrared spectroscopy confirmed the presence of peaks from 700-4000 cm−1 correlating to AgNPs. Presence of silver, carbon and oxygen was confirmed by X-ray photoelectron spectroscopy and Energy-dispersive X-ray spectroscopy. Transmission electron microscopy showed a uniform spherical particle in the size of 100 nm, and scanning electron microscope showed spherical particles at a magnification of 100 µm. The extracts and the synthesized AgNPs were tested for cytotoxicity and anti-cancer activity against the Vero and U87 glioma cell lines. The results for both cell lines indicated that dichloromethane extract and AgNPs were cytotoxic and had potential anti-cancer properties. [ABSTRACT FROM AUTHOR]