부산대학교 도서관

Introduction: As 2D-speckle tracking echocardiography (STE) has supposed to be a novel and non-invasive imaging modality for the early recognition of ischemic heart disease before angiography, further study of this diagnostic method is of great importance. Aim: This study was intended to weigh the diagnostic value of STE in the revealing of myocardial ischemia before and after efficacious revascularization. Material and methods: 25 patients with an indication for revascularization - angioplasty or coronary artery bypass grafting (CABG) - diagnosed by an experienced cardiologist and based on accepted criteria, underwent two-dimensional (2D) STE; and global systolic longitudinal strain for each of the sections in the apical 2-chamber and 4-chamber views was evaluated. Results and discussion: The mean of longitudinal strain before revascularization procedures was 14.94% ± 2.32% and after procedures was 19.08% ± 2.83%. (P < 0.001). After procedure, 6 patients (24%) showed longitudinal strain under 18% in spite of revascularization; mean longitudinal strain was significantly lower in these 6 patients compared to other 19 patients who revealed longitudinal strain over 18% after revascularization (15.45% ± 2.35% vs. 20.22% ± 1.84%, P < 0.001). We found that the sensitivity and specificity of longitudinal strain differences at the cut-off point 4.1% for predicting ischemia with 0.281 area under the ROC curve were 100%, 53%, 40%, 100%, and 64%, respectively. Conclusions: Our results showed that predicting and diagnosing myocardial ischemia by STE is a precise method with high sensitivity and specificity values. [ABSTRACT FROM AUTHOR]