학술논문
Diagnostic value of ultra-deep targeted next-generation sequencing in patients with suspect pancreatic and periampullary lesions.
Document Type
Article
Author
Source
Subject
*NUCLEOTIDE sequencing
*SURGICAL excision
*PATIENT selection
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Language
ISSN
1365-182X
Abstract
B Background: b Radiologic imaging and morphological cytology assessment have limitations for preoperative classification of pancreatic and periampullary lesions, often resulting in surgical resection without definitive diagnosis. In 4 patients, the NGS results were negative but did not influence the treatment plan as sampling error of cytology was suspected; NGS analysis on resection material revealed pathogenic variants in all 4 patients. B Conclusion: b In our study, NGS analysis changed the treatment plan in 10% of the patients. [Extracted from the article]