학술논문

Epidemiological Determinants of Advanced Prostate Cancer in Elderly Men in the United States.
Document Type
Article
Source
Clinical Medicine Insights: Oncology. 6/26/2019, Vol. 13, pN.PAG-N.PAG. 1p. 2 Charts, 2 Graphs.
Subject
*CENSUS
*CLUSTER analysis (Statistics)
*HEALTH behavior
*HEALTH services accessibility
*HELP-seeking behavior
*MEDICARE
*POPULATION geography
*PREVENTIVE health services
*PROSTATE tumors
*PUBLIC health surveillance
*RACE
*TUMOR classification
*COMORBIDITY
*LOGISTIC regression analysis
*PROSTATE-specific antigen
*SOCIOECONOMIC factors
*LIFESTYLES
*DEMOGRAPHIC characteristics
*FAMILY history (Medicine)
*HEALTH & social status
*DESCRIPTIVE statistics
*EARLY detection of cancer
*CLUSTER sampling
*OLD age
Language
ISSN
1179-5549
Abstract
In this study, we examined the effects of individual-level and area-level characteristics on advanced prostate cancer diagnosis among Medicare eligible older men (ages 70+ years). We analyzed patients from the linked Surveillance, Epidemiology, and End Results (SEER)-Medicare database (2000-2007) linked to US Census and County Business Patterns data. Cluster-adjusted logistic regression models were used to quantify the effects of individual preventive health behavior, clinical and demographic characteristics, area-level health services supply, and socioeconomic characteristics on stage at diagnosis. The fully adjusted model was used to estimate county-specific effects and predicted probabilities of advanced prostate cancer. In the adjusted analyses, low intensity of annual prostate-specific antigen (PSA) testing and other preventive health behavior, high comorbidity, African American race, and lower county socioeconomic and health services supply characteristics were statistically significantly associated with a higher likelihood of distant prostate cancer diagnosis. The fully adjusted predicted proportions of advanced prostate cancer diagnosis across 158 counties ranged from 3% to 15% (mean: 6%, SD: 7%). County-level socioeconomic and health services supply characteristics, individual-level preventive health behavior, demographic and clinical characteristics are determinants of advanced stage prostate cancer diagnosis among older Medicare beneficiaries; other health care-related factors such as family history, lifestyle choices, and health-seeking behavior should also be considered as explanatory factors. [ABSTRACT FROM AUTHOR]