학술논문

Individualized Ablation of Hepatocellular Carcinoma: Tailored Approaches across the Phenotype Spectrum.
Document Type
Article
Source
Seminars in Interventional Radiology. 2019, Vol. 36 Issue 4, p287-297. 11p.
Subject
*HEPATOCELLULAR carcinoma
*LENGTH of stay in hospitals
*MEDICAL care costs
*PHENOTYPES
*TREATMENT effectiveness
*ABLATION techniques
Language
ISSN
0739-9529
Abstract
Ablation is now recommended by international guidelines for the definitive treatment of hepatocellular carcinoma (HCC). Extensive clinical studies have demonstrated outcomes comparable to surgical resection with shorter hospital stays, decreased costs, and improved quality of life. Successful ablation requires complete treatment of both tumor and margin while preserving critical adjacent structures. HCC exhibits highly variable presentations in both anatomic involvement and biology which have significant implications on choice of ablative therapy. There are now abundant ablation modalities and adjunctive techniques which can be used to individualize ablation and maximize curative results. This article provides a patient-centered summary of approaches to HCC ablation in the context of patient performance, hepatic reserve, tumor phenotype and biology, intra- and extrahepatic anatomy, and ablation technology. [ABSTRACT FROM AUTHOR]