학술논문
Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup.
Document Type
Article
Author
Raina, Rupesh; Grewal, Manpreet K; Blackford, Martha; Symons, Jordan M.; Somers, Michael J. G.; Licht, Christoph; Basu, Rajit K; Sethi, Sidharth Kumar; Chand, Deepa; Kapur, Gaurav; McCulloch, Mignon; Bagga, Arvind; Krishnappa, Vinod; Yap, Hui-Kim; de Sousa Tavares, Marcelo; Bunchman, Timothy E; Bestic, Michelle; Warady, Bradley A; de Ferris, Maria Díaz-González
Source
Subject
*ACETAMINOPHEN
*AMINOGLYCOSIDES
*BARBITURATES
*CARBAMAZEPINE
*INFORMATION storage & retrieval systems
*MEDICAL databases
*MEDICAL information storage & retrieval systems
*KIDNEY diseases
*MEDICAL protocols
*MEDLINE
*METHOTREXATE
*NEPHROTOXICOLOGY
*ONLINE information services
*PEDIATRICS
*PHENYTOIN
*POISONING
*SALICYLATES
*THEOPHYLLINE
*THERAPEUTICS
*VALPROIC acid
*VANCOMYCIN
*SYSTEMATIC reviews
*LITHIUM compounds
*METFORMIN
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Language
ISSN
0931-041X
Abstract
Background: Intentional or unintentional ingestions among children and adolescents are common. There are a number of ingestions amenable to renal replacement therapy (RRT). Methods: We systematically searched PubMed/Medline, Embase, and Cochrane databases for literature regarding drugs/intoxicants and treatment with RRT in pediatric populations. Two experts from the PCRRT (Pediatric Continuous Renal Replacement Therapy) workgroup assessed titles, abstracts, and full-text articles for extraction of data. The data from the literature search was shared with the PCRRT workgroup and two expert toxicologists, and expert panel recommendations were developed. Results and Conclusions: We have presented the recommendations concerning the use of RRTs for treatment of intoxications with toxic alcohols, lithium, vancomycin, theophylline, barbiturates, metformin, carbamazepine, methotrexate, phenytoin, acetaminophen, salicylates, valproic acid, and aminoglycosides. [ABSTRACT FROM AUTHOR]