학술논문
Effects of Coffee, Black Tea and Green Tea Consumption on the Risk of Non-Hodgkin's Lymphoma: A Systematic Review and Dose–Response Meta-Analysis of Observational Studies.
Document Type
Article
Source
Subject
*LYMPHOMA risk factors
*COFFEE
*CONFIDENCE intervals
*DOSE-response relationship in biochemistry
*DRINKING (Physiology)
*INFORMATION storage & retrieval systems
*MEDICAL databases
*MEDLINE
*META-analysis
*ONLINE information services
*TEA
*SYSTEMATIC reviews
*GREEN tea
*EFFECT sizes (Statistics)
*RELATIVE medical risk
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Language
ISSN
0163-5581
Abstract
Aim: Several studies have evaluated the association between coffee, black and green tea consumption and non-Hodgkin's lymphoma (NHL) risk, while the results were inconsistent. We conducted a dose–response meta-analysis of available observational studies to assess the association among coffee, black and green tea intake and the risk of NHL in the general population. Methods: Studies published up to August 2018 were identified on the basis of a literature search in PubMed, ISI Web of Science, Scopus and Cochrane databases using Mesh and non-Mesh relevant keywords. Relative risks (RRs) with 95% confidence intervals (CIs) and the dose–response relationships were calculated using random-effects models. Results: In the meta-analysis of 19 effect sizes (315,972 participants with 4,914 cases of NHL), we found that higher green tea intake was associated with a 39% reduced risk of NHL (pooled RR = 0.61; 95% CIs = 0.38–0.99, I2=60.4%, pheterogeneity=0.080) in high- versus low-intake meta-analysis. No association was observed between coffee intake (pooled RR = 1.21; 95% CIs = 0.97–1.50, I2=52.6%, pheterogeneity < 0.05), black tea intake (pooled RR = 1.01; 95% CI = 0.82–1.24, I2=0%, pheterogeneity=0.875) and risk of NHL in high- versus low-intake meta-analysis. Conclusions: Findings from this dose–response meta-analysis suggest that green tea intake may be associated with reduced risk of NHL. [ABSTRACT FROM AUTHOR]