부산대학교 도서관

The objective of this study was to determine the prevalence of antibiotic resistant nontyphoidal Salmonella in 39 retail chicken meat shops located in 7 towns of North India. Overall, nontyphoidal Salmonella prevalence of 9.43% (70/742) was observed. Highest Salmonella prevalence was observed in Lalkuan (20.99%). Chicken meat samples (40%) showed highest Salmonella prevalence followed by poultry feces (20%). Three serotypes of Salmonella were identified, Salmonella Kentucky (S.Kentucky, 74.29%), Salmonella Virchow (S.Virchow, 17.14%) and Salmonella Typhimurium (S.Typhimurium, 7.14%). All isolates were multidrug resistant (MDR) by disk-diffusion assay, showing resistance to three or more classes of antibiotics. High resistance was observed to tetracycline (100%), erythromycin (100%), nalidixic acid (98.57%), ampicillin (95.71%) and ciprofloxacin (82.86%). Fifty-one (98.08%) S. Kentucky isolates were resistant to ciprofloxacin. Of these, 49 S. Kentucky isolates showed MIC values in the range of 3 to >256 μg/ml. Twenty-nine (41.43%) Salmonella isolates were co-resistant to ciprofloxacin and cefotaxime by disk-diffusion test. The tet A gene was detected in all Salmonella isolates and the bla TEM was the most predominant (25.37%) β-lactam gene. Multiple virulence genes such as sip A, mgt C, s op E1, s tn , sop B, fli C, spv C and gip A were also detected. High resistance to quinolone, cephalosporin and tetracycline antibiotics in nontyphoidal Salmonella isolates of poultry origin points towards their extra-label use in poultry farms. • Salmonella Kentucky as the predominant serotype in retail chicken shops. • All Salmonella isolates (100%) are multidrug resistant. • 41.43% Salmonella isolates co-resistant to ciprofloxacin and cefotaxime. • High ciprofloxacin and levofloxacin MICs. • bla TEM (25.37%) is the most predominant β-lactam gene detected. [ABSTRACT FROM AUTHOR]