부산대학교 도서관

A new selective fluorescent sensor for detection of dopamine (DA) using Co2+ -decorated thioglycolic acid-capped CdS QDs (Co2+@TGA-CdS QDs) was proposed. Basically, the fluorescent intensity of TGA-CdS QDs can be quenched by Co2+. However, with the addition of dopamine into the solution of Co2+@TGA-CdS QDs, the fluorescent intensity was efficiently quenched due to the formation of the efficient quencher (Co2+-dopamine complex). Thus, the concentration of dopamine can be determined by tracking the decrease in the fluorescent intensity of the Co2+@TGA-CdS QDs. The proposed sensor showed high selectivity towards the detection of dopamine over other catecholamine derivatives and related compounds. Under optimal conditions, the quenching efficiency of dopamine on the Co2+@TGA-CdS QDs system was linearly proportional to the concentration of dopamine in the range of 20-100μmoll-1. The limits of detection and quantification were 1.8 and 12.7μmoll-1, respectively. This sensor system was demonstrated to detect dopamine in real urine samples with satisfactory results. [ABSTRACT FROM AUTHOR]