학술논문
Plasmodium falciparum Plasmepsin 2 Duplications, West Africa.
Document Type
Journal Article
Author
Source
Subject
*PLASMODIUM
*ANTIMALARIALS
*DRUG efficacy
*AFRICANS
*HEALTH
INFECTION treatment
*
*
*
*
Language
ISSN
1080-6040
Abstract
Dihydroartemisinin/piperaquine (DHA/PPQ) is increasingly deployed as antimalaria drug in Africa. We report the detection in Mali of Plasmodium falciparum infections carrying plasmepsin 2 duplications (associated with piperaquine resistance) in 7/65 recurrent infections within 2 months after DHA/PPQ treatment. These findings raise concerns about the long-term efficacy of DHA/PPQ treatment in Africa. [ABSTRACT FROM AUTHOR]