학술논문
Longitudinal cancer risk management trajectories of BRCA1/2 mutation-positive reproductive-age women.
Document Type
Article
Author
Source
Subject
*TUMOR risk factors
*BREASTFEEDING
*CANCER patient medical care
*LONGITUDINAL method
*MEDICAL care
*GENETIC mutation
*REPRODUCTIVE health
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Language
ISSN
0734-7332
Abstract
Young women withBRCA1/2mutations face difficult health-care decisions regarding family formation, fertility, breastfeeding, and whether/when to undergo cancer risk-reducing surgery. This longitudinal qualitative study investigated these life choices during the reproductive years. We conducted two semistructured interviews over three years with 12 reproductive-ageBRCA1/2-positive women. Researchers coded transcripts to examine the evolution of risk perceptions, risk management, and family planning decisions. To cope with the conflict between cancer risk reduction versus plans for pregnancy, breastfeeding, and child rearing, participants deliberately prioritized either risk reducing surgery or family formation goals. Implications for mutation carriers and health-care providers are outlined. [ABSTRACT FROM AUTHOR]