학술논문
Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.
Document Type
Article
Author
Holzinger, Emily R.; Verma, Shefali S.; Moore, Carrie B.; Hall, Molly; De, Rishika; Gilbert-Diamond, Diane; Lanktree, Matthew B.; Pankratz, Nathan; Amuzu, Antoinette; Burt, Amber; Dale, Caroline; Dudek, Scott; Furlong, Clement E.; Gaunt, Tom R.; Seung Kim, Daniel; Riess, Helene; Sivapalaratnam, Suthesh; Tragante, Vinicius; van Iperen, Erik P. A.; Brautbar, Ariel
Source
Subject
*LIPIDS
*DYSLIPIDEMIA
*REGRESSION analysis
*GENETICS
*GENOMES
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Language
ISSN
1756-0381
Abstract
The article provides information on the study based on genetic interactions linked to circulating lipid levels. Topics discussed include impact of dyslipidemia on human health and genetic components of lipids, genetic architecture of complex traits, genome-wide interaction study (GWIS), and linear regression models.