학술논문
Antibiotic Resistance Pattern of Extended-Spectrum Beta-Lactamases-Producing Klebsiella pneumoniae Clinical Isolates from Zahedan, Southeast Iran.
Document Type
Article
Author
Source
Subject
*DRUG resistance in bacteria
*KLEBSIELLA pneumoniae
*ANTIBIOTICS
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*
Language
ISSN
2008-7977
Abstract
Background: Resistance to various classes of antibiotics iscommonamong extended-spectrum beta-lactamases (ESBLs)-producing bacteria. Objectives: To determine the antibiotic resistance pattern of ESBLs-producing K. pneumoniae clinical isolates from Zahedan. Methods: In this sectional-descriptive study, susceptibility of 51 ESBLs-producing K. pneumoniae isolates to 18 antimicrobial agents was determined. Results: All isolates were resistant to cefotaxime, cefpodoxime and amoxicillin as well as susceptible to colistin sulfate. Also, most isolates were resistant to trimethoprim/sulfamethoxazole and aztreonam. Conclusions: Our findings demonstrated that the rate of resistance to beta-lactams, sulfonamides, tetracyclines, aminoglycosides and fluoroquinolones in ESBLs-producing K. pneumoniae isolates is high in Zahedan. [ABSTRACT FROM AUTHOR]