학술논문
One-pot synthesis of oxoisoindoline-1,2,3-triazole hybrid by a Ugi–click reaction.
Document Type
Article
Author
Source
Subject
*TRIAZOLES synthesis
*BENZOIC acid
*PROPARGYLAMINES
*CHEMICAL reactions
*CATALYTIC activity
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Language
ISSN
0039-7911
Abstract
1,2,3-Triazole-3-oxoisoindoline-1-carboxamide system was successfully synthesized by using a combination of Ugi and click reactions. This two-step, one-pot synthesis was started by the reaction of 2-formyl benzoic acid, propargyl amine, and cyclohexyl isocyanide in ethanol. The resultant Ugi adduct underwent a copper-catalyzed click reaction, producing the desired products in good yields. [ABSTRACT FROM PUBLISHER]