부산대학교 도서관

Nt-Sd- RLK encodes an S-domain lectin receptor-like kinase that is induced in response to microbe-associated molecular pattern molecules ( MAMPs) such as lipopolysaccharide ( LPS). In this study, we investigated the alternative splicing of Nt-Sd- RLK in response to LPS stimulation. Our data indicate that in nonstimulated cells, a shorter transcript of Nt-Sd- RLK is generated and that in response to LPS, alternative splicing produces the full-length transcript. We propose that the extracellular domain of Nt-Sd- RLK encoded by the shorter transcript functions in pathogen surveillance. Once this domain binds LPS, alternative splicing generates the kinase domain-containing Nt-Sd- RLK that activates downstream signalling leading to a defence response. Thus, our findings suggest that plant defence signalling may be regulated through the alternative splicing of receptor-like kinases involved in pathogen recognition. [ABSTRACT FROM AUTHOR]