부산대학교 도서관

In recent years, there has been a significant increase in the incidence of human fungal infections. The increase in cases of infection caused byCandidaspecies, and the consequent excessive use of antimicrobials, has favored the emergence of resistance to conventional antifungal agents over the past decades. Consequently,Candidainfections morbidity and mortality are also increasing. Therefore, new approaches are needed to improve the outcome of patients suffering fromCandidainfections, because it seems unlikely that the established standard treatments will drastically lower the morbidity of mucocutaneousCandidainfections and the high mortality associated with invasive candidiasis. This review aims to present the last advances in the traditional antifungal therapy, and present an overview of novel strategies that are being explored for the treatment ofCandidainfections, with a special focus on combined antifungal agents, antifungal therapies with alternative compounds (plant extracts and essential oils), adjuvant immunotherapy, photodynamic therapy and laser therapy. [ABSTRACT FROM AUTHOR]