학술논문
Tetracyanoethene and 1-Amino-1,2,2-ethenetricarbonitrile in the Synthesis of Heterocycles of Prospective Antioxidant and Antibacterial.
Document Type
Article
Source
Subject
*TETRACYANOETHYLENE
*PIPERIDINE
*ALIPHATIC amine synthesis
*DIOXANE
*ANTIOXIDANTS
*ANTI-infective agents
*
*
*
*
*
Language
ISSN
0022-152X
Abstract
Reaction of 1,1,2,2-ethenetetracarbonitrile (TCNE) with aroyl thioureas in dioxane catalyzed by few drops of piperidine, led to the corresponding 1,2,4-oxathiazoles. Under the same reaction condition, thiosemicarbazide or thiosemicarbazone reacted with either TCNE or 1-amino-1,2,2-ethene-tricarbonitrile. The structures of the products were elucidated via NMR, IR, mass spectra, and elemental analyses. The mechanism of formation was discussed. Biological (against Gram-positive and Gram-negative bacteria) and antioxidant activities were tested. Some of these heterocyclic compounds showed high activity as antioxidant and antibacterial compounds. The was investigated. [ABSTRACT FROM AUTHOR]