부산대학교 도서관

Background Sleep complaints are frequent among chronic kidney disease ( CKD) patients. Objective We aimed to subjectively and objectively assess sleep disturbances in CKD patients and compare them between those who undergo hemodialysis (HD) and those who do not. Patients and methods The study was conducted on 40 CKD patients who were subdivided into two groups; group I included patients not undergoing HD (n = 20), and group II included patients on regular HD (n = 20). A total of 20 matched healthy volunteers participated as controls. Patients completed Epworth Sleepiness Scale, a sleep questionnaire, and underwent an attended polysomnography. Results All patients had sleep complaints in the form of excessive daytime sleepiness, diffi culty falling asleep, early morning awakening, jerking leg movements, and fragmented sleep. CKD patients had lower total sleep time, sleep effi ciency, slow wave sleep (SWS) percentage, oxygen desaturation, and higher respiratory distress and periodic limb movement ( PLM) indices compared with controls. Group II patients showed a higher Epworth Sleepiness Scale and more frequent complaints of leg jerks. Furthermore, group II patients showed higher sleep effi ciency and PLM compared with group I. Patients' age positively correlated with respiratory distress index and negatively correlated with total sleep time and oxygen saturation. The duration of illness and duration of dialysis positively correlated with the number of awakenings. Conclusion There is a high prevalence of sleep disorders in CKD patients whether they were on regular PLMs. Achieving a more complete understanding of sleep problems experienced by these patients can improve quality of life and patient survival. [ABSTRACT FROM AUTHOR]