학술논문
Complementary Role of Ultrasound in Management of Gestational Trophoblastic Disease.
Document Type
Article
Author
Source
Subject
*DOPPLER ultrasonography
*CHI-squared test
*CHORIONIC gonadotropins
*ENDOSCOPIC ultrasonography
*LONGITUDINAL method
*PROBABILITY theory
*T-test (Statistics)
*DATA analysis software
*DESCRIPTIVE statistics
*GESTATIONAL trophoblastic disease
*MANN Whitney U Test
*DISEASE complications
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Language
ISSN
1735-1065
Abstract
Background: Transvaginal Ultrasonography is a noninvasive and inexpensive medical imaging tool used for the diagnosis of various diseases. Objectives: To identify an effective method to identify high-risk patients for developing malignancy after molar evacuation. Patients and Methods: A prospective serial assessment of 19 patients with gestational trophoblastic disease was performed. Clinical and laboratory data, transvaginal ultrasound and Doppler findings were evaluated the day before evacuation. They were followed-up in the first week after evacuation and every two weeks during the next two months, then every month until the sixth month. Results: Ovarian theca lutein cysts (P = 0.018) (among pre-evacuation factors) and first week ultrasound (P =0.02) can help in detecting high-risk patients. Even though, when β-hCG titer is not available in a high-risk patient, post evacuation myometrial involvement (P = 0.005) is a useful sign for detecting persistency. Conclusions: Some ultrasonographic features of molar pregnancy have capability to predict malignancy in the course of disease. [ABSTRACT FROM AUTHOR]