부산대학교 도서관

: PurposeTo investigate outcomes in premature infants with high-risk retinopathy of prematurity and secondary vitreous hemorrhage.: DesignRetrospective chart review.: MethodsPatients were selected from a database of infants undergoing retinopathy of prematurity screening from September 1997 to November 1999. Infants with high-risk retinopathy of prematurity (zone I or posterior zone II threshold disease) with and without vitreous hemorrhage were compared.: Main outcome measuresFinal stage of retinopathy of prematurity and short-term structural outcome were assessed. Visual acuity and refraction were measured when possible.: ResultsTwenty-two eyes of 11 patients (group 1) had high-risk (posterior zone II or zone I threshold) retinopathy of prematurity without vitreous hemorrhage. Group 1 patients had a 91% favorable short-term structural outcome. Eight eyes of five infants developed vitreous hemorrhage with high-risk retinopathy of prematurity (group 2). Group 2 patients had only a 12.5% favorable short-term structural outcome. Seven of eight (87.5%) progressed to stage IVa or IVb retinopathy of prematurity. Six eyes underwent vitreoretinal surgery after a median duration of hemorrhage of 36 ± 29 days (4–70 days). Three eyes developed stage V detachments and three progressed to phthisical degeneration. Final visual acuity was no light perception in three eyes.: ConclusionVitreous hemorrhage, in association with advanced retinopathy of prematurity, is a poor prognostic sign. [Copyright &y& Elsevier]