부산대학교 도서관

Dahlqvist, Johanna; Fulco, Charles P; Ray, John P; Liechti, Thomas; Boer, Carl G de; Lieb, David J; Eisenhaure, Thomas M; Engreitz, Jesse M; Roederer, Mario; Hacohen, Nir

Human Molecular Genetics; 6/15/2022, Vol. 31 Issue 12, p1946-1961, 16p

Martyn GE; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA.; Montgomery MT; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA.; Jones H; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA.; Guo K; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA.; Doughty BR; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Linder J; Calico Life Sciences LLC, South San Francisco, CA 94080, USA.; Bisht D; Department of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA.; Xia F; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA.; Cai XS; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Chen Z; Department of Computer Science, Stanford University, Stanford, CA 94305, USA.; Cochran K; Department of Computer Science, Stanford University, Stanford, CA 94305, USA.; Lawrence KA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Munson G; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Pampari A; Department of Computer Science, Stanford University, Stanford, CA 94305, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Sahni N; Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77230, USA; Quantitative and Computational Biosciences Program, Baylor College of Medicine, Houston, TX 77030, USA.; Kelley DR; Calico Life Sciences LLC, South San Francisco, CA 94080, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Biology, MIT, Cambridge, MA 02139, USA; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Computer Science, Stanford University, Stanford, CA 94305, USA.; Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA 94305, USA; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA. Electronic address: engreitz@stanford.edu.

Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

Iyer AR; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Gurumurthy A; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Chu SA; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Kodgule R; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Aguilar AR; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Saari T; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Ramzan A; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Rosa J; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Gupta J; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Emmanuel A; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Hall CN; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Runge JS; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Owczarczyk AB; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Cho JW; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Weiss MB; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Anyoha R; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts.; Sikkink K; Arima Genomics, Carlsbad, California.; Gemus S; Arima Genomics, Carlsbad, California.; Fulco CP; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts.; Perry AM; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Schmitt AD; Arima Genomics, Carlsbad, California.; Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, California.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, California.; Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Brown NA; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Cieslik MP; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.; Ryan RJH; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan.

Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

Rahmat M; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Clement K; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.; Alberge JB; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Sklavenitis-Pistofidis R; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Kodgule R; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Heilpern-Mallory D; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.; Nilsson K; Department of Biochemistry, Northeastern University, Boston, Massachusetts.; Dorfman D; Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Department of Genetics, Stanford University School of Medicine, Stanford, California.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford, California.; Getz G; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Cancer Center, Massachusetts General Hospital, Charlestown, Massachusetts.; Pinello L; Harvard Medical School, Boston, Massachusetts.; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Ryan RJH; Department of Pathology, University of Michigan, Ann Arbor, Michigan.; Ghobrial IM; Dana-Farber Cancer Institute, Boston, Massachusetts.; Harvard Medical School, Boston, Massachusetts.

Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

Guckelberger P; Doughty BR; Munson G; Rao SSP; Tan Y; Cai XS; Fulco CP; Nasser J; Mualim KS; Bergman DT; Ray J; Jagoda E; Munger CJ; Gschwind AR; Sheth MU; Tan AS; Pulido SG; Mitra N; Weisz D; Shamim MS; Durand NC; Mahajan R; Khan R; Steinmetz LM; Kanemaki MT; Lander ES; Meissner A; Aiden EL; Engreitz JM

Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Martyn GE; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA.; Montgomery MT; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA.; Jones H; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA.; Guo K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA.; Doughty BR; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Linder J; Calico Life Sciences, South San Francisco, CA, USA.; Chen Z; Department of Computer Science, Stanford University, Stanford, CA, USA.; Cochran K; Department of Computer Science, Stanford University, Stanford, CA, USA.; Lawrence KA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Munson G; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Pampari A; Department of Computer Science, Stanford University, Stanford, CA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Present Address: Sanofi, Cambridge, MA, USA.; Kelley DR; Calico Life Sciences, South San Francisco, CA, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA.; Engreitz JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Basic Science and Engineering Initiative, Stanford Children's Health, Betty Irene Moore Children's Heart Center, Stanford, CA, USA.; The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA.

Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Ray JP; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; de Boer CG; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.; Lareau CA; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA.; Kanai M; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.; Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, 02115, USA.; Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA.; Tewhey R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, 02138, USA.; Ludwig LS; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Reilly SK; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, 02138, USA.; Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Harvard Society of Fellows, Harvard University, Cambridge, MA, 02138, USA.; Issner R; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Finucane HK; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, 02114, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, 02115, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA.; Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Howard Hughes Medical Institute, Cambridge, MA, 02142, USA. aregev@broadinstitute.org.; Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. nhacohen@mgh.harvard.edu.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, 02114, USA. nhacohen@mgh.harvard.edu.

Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

Weeks EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. eweeks@broadinstitute.org.; Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, USA.; Artificial Intelligence Laboratory, Illumina, Inc., San Diego, CA, USA.; Cheng NY; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Trippe BL; Program in Computational & Systems Biology, MIT, Cambridge, MA, USA.; Computer Science & Artificial Intelligence Lab, MIT, Cambridge, MA, USA.; Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Vertex Pharmaceuticals Incorporated, Boston, MA, USA.; Miao J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Patwardhan TA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, Harvard University, Cambridge, MA, USA.; Kanai M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, MGH, Boston, MA, USA.; Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, USA.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bristol Myers Squibb, Cambridge, MA, USA.; Tashman KC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Li T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; MD-PhD Program, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Ordovas-Montanes J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Gastroenterology, Hepatology, and Nutrition, Boston Children's Hospital, Boston, MA, USA.; Program in Immunology, Harvard Medical School, Boston, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Smillie CS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Computational & Systems Biology, MIT, Cambridge, MA, USA.; Biton M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Molecular Biology, MGH, Boston, MA, USA.; Department of Biological Regulation, Weizmann Institute of Science, Rehovot, Israel.; Shalek AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Institute for Medical Engineering and Science, MIT, Cambridge, MA, USA.; Department of Chemistry, MIT, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Ragon Institute of MGH, MMIT, Cambridge, MA, USA.; Ananthakrishnan AN; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, MGH, Boston, MA, USA.; Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Molecular Biology, MGH, Boston, MA, USA.; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, MGH, Boston, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.; Regev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA.; Howard Hughes Medical Institute, MIT, Cambridge, MA, USA.; Genentech, San Francisco, CA, USA.; Gupta RM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Cardiovascular Medicine and Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Lage K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Surgery, MGH, Boston, MA, USA.; Ardlie KG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.; Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA.; Finucane HK; Broad Institute of MIT and Harvard, Cambridge, MA, USA. finucane@broadinstitute.org.; Analytic and Translational Genetics Unit, MGH, Boston, MA, USA. finucane@broadinstitute.org.

Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Iyer AR; Gurumurthy A; Kodgule R; Aguilar AR; Saari T; Ramzan A; Rausch D; Gupta J; Hall CN; Runge JS; Weiss M; Rahmat M; Anyoha R; Fulco CP; Ghobrial IM; Engreitz J; Cieslik MP; Ryan RJH

Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

Bick, Alexander G; Weinstock, Joshua S; Nandakumar, Satish K; Fulco, Charles P; Leventhal, Matthew J; Bao, Erik L; Nasser, Joseph; Zekavat, Seyedeh M; Szeto, Mindy D; Laurie, Cecelia; Taub, Margaret A; Mitchell, Braxton D; Barnes, Kathleen C; Moscati, Arden; Fornage, Myriam; Redline, Susan; Psaty, Bruce M; Silverman, Edwin K; Weiss, Scott T; Palmer, Nicholette D; Vasan, Ramachandran S; Burchard, Esteban G; Kardia, Sharon LR; He, Jiang; Kaplan, Robert C; Smith, Nicholas L; Arnett, Donna K; Schwartz, David A; Correa, Adolfo; de Andrade, Mariza; Guo, Xiuqing; Konkle, Barbara A; Custer, Brian; Peralta, Juan M; Gui, Hongsheng; Meyers, Deborah A; McGarvey, Stephen T; Chen, Ida Yii-Der; Shoemaker, M. Benjamin; Peyser, Patricia A; Broome, Jai G; Gogarten, Stephanie M; Wang, Fei Fei; Wong, Quenna; Montasser, May E; Daya, Michelle; Kenny, Eimear E; North, Kari; Launer, Lenore J; Cade, Brian E; Bis, Joshua C; Cho, Michael H; Lasky-Su, Jessica; Bowden, Donald W; Cupples, L Adrienne; Mak, Angel CY; Becker, Lewis C; Smith, Jennifer A; Kelly, Tanika N; Aslibekyan, Stella; Heckbert, Susan R; Tiwari, Hemant K; Yang, Ivana V; Heit, John A; Lubitz, Steven A; Rich, Stephen S; Johnsen, Jill M; Curran, Joanne E; Wenzel, Sally; Weeks, Daniel E; Rao, Dabeeru C; Darbar, Dawood; Moon, Jee-Young; Tracy, Russell P; Buth, Erin J; Rafaels, Nicholas; Loos, Ruth JF; Hou, Lifang; Lee, Jiwon; Kachroo, Priyadarshini; Freedman, Barry I; Levy, Daniel; Bielak, Lawrence F; Hixson, James E; Floyd, James S; Whitsel, Eric A; Ellinor, Patrick; Irvin, Marguerite R; Fingerlin, Tasha E; Raffield, Laura M; Armasu, Sebastian M; Rotter, Jerome I; Wheeler, Marsha M; Sabino, Ester C; Blangero, John; Williams, L. Keoki; Levy, Bruce D; Sheu, Wayne Huey-Herng; Roden, Dan M; Boerwinkle, Eric; Manson, JoAnn E; Mathias, Rasika A; Desai, Pinkal; Taylor, Kent D; Johnson, Andrew; Auer, Paul L; Kooperberg, Charles; Laurie, Cathy C; Blackwell, Thomas W; Smith, Albert V; Zhao, Hongyu; Lange, Ethan; Lange, Leslie; Wilson, James G; Lander, Eric S; Engreitz, Jesse M; Ebert, Benjamin L; Reiner, Alexander P; Sankaran, Vijay G; Jaiswal, Sidd; Abecasis, Goncalo; Natarajan, Pradeep; Kathiresan, Sekar

Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Geisel School of Medicine at Dartmouth, Hanover, NH, USA.; Jones TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Liu V; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Ray J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Jagoda E; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Siraj L; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Biophysics Graduate Program, Harvard University, Cambridge, MA, USA.; Kang HY; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kane M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Rios A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Nguyen TH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Grossman SR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bristol Myers Squibb, Cambridge, MA, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. engreitz@stanford.edu.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. engreitz@stanford.edu.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA. engreitz@stanford.edu.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Gazal S; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. gazal@usc.edu.; Center for Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. gazal@usc.edu.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. gazal@usc.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. gazal@usc.edu.; Weissbrod O; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Hormozdiari F; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Dey KK; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Jagadeesh KA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Weiner DJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Shi H; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Bristol Myers Squibb, Cambridge, MA, USA.; O'Connor LJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Pasaniuc B; Departments of Computational Medicine, Human Genetics, Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA.; Price AL; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. aprice@hsph.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. aprice@hsph.harvard.edu.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA. aprice@hsph.harvard.edu.

Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Oren Y; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.; Tsabar M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA, USA.; Cuoco MS; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Amir-Zilberstein L; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cabanos HF; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Departments of Medicine, Harvard Medical School, Boston, MA, USA.; Hütter JC; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Hu B; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Thakore PI; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, South San Francisco, CA, USA.; Tabaka M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bristol Myers Squibb, Cambridge, MA, USA.; Colgan W; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Cuevas BM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Hurvitz SA; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.; Slamon DJ; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.; Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.; Deik A; Metabolomics Platform, Broad Institute, Cambridge, MA, USA.; Pierce KA; Metabolomics Platform, Broad Institute, Cambridge, MA, USA.; Clish C; Metabolomics Platform, Broad Institute, Cambridge, MA, USA.; Hata AN; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Departments of Medicine, Harvard Medical School, Boston, MA, USA.; Zaganjor E; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, USA.; Lahav G; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Politi K; Section of Medical Oncology, Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Yale Cancer Center, New Haven, CT, USA.; Brugge JS; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. joan_brugge@hms.harvard.edu.; Ludwig Center at Harvard, Boston, MA, USA. joan_brugge@hms.harvard.edu.; Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. aviv.regev.sc@gmail.com.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. aviv.regev.sc@gmail.com.; Genentech, South San Francisco, CA, USA. aviv.regev.sc@gmail.com.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bristol Myers Squibb, Cambridge, MA, USA.; Guckelberger P; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, Berlin, Germany.; Doughty BR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Patwardhan TA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Statistics, Harvard University, Cambridge, MA, USA.; Jones TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Nguyen TH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ulirsch JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, USA.; Lekschas F; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Mualim K; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Natri HM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Weeks EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Munson G; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kane M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kang HY; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA.; Cui A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, MA, USA.; Ray JP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Systems Immunology, Benaroya Research Institute at Virginia Mason, Seattle, WA, USA.; Eisenhaure TM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Collins RL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Dey K; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Pfister H; Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.; Price AL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.; Epstein CB; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA.; Xavier RJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.; Department of Molecular Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Daly MJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.; Huang H; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Finucane HK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Hacohen N; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Center for Cancer Research, Massachusetts General Hospital, Boston, MA, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA. lander@broadinstitute.org.; Department of Biology, MIT, Cambridge, MA, USA. lander@broadinstitute.org.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA. lander@broadinstitute.org.; Office of Science and Technology Policy, Executive Office of the President, White House, Washington, DC, USA. lander@broadinstitute.org.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. engreitz@stanford.edu.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. engreitz@stanford.edu.; BASE Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA, USA. engreitz@stanford.edu.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Bick AG; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Weinstock JS; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Nandakumar SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Bao EL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Health Sciences and Technology Program, Harvard Medical School, Boston, MA, USA.; Zekavat SM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Yale School of Medicine, New Haven, CT, USA.; Szeto MD; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Medical Scientist Training Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Liao X; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Leventhal MJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Chang K; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Laurie C; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Burugula BB; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.; Gibson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Niroula A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Lin AE; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Taub MA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ardlie K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA.; Barnes KC; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.; Moscati A; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Redline S; Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Silverman EK; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Weiss ST; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Vasan RS; Departments of Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, USA.; Burchard EG; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, USA.; Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.; Tulane University Translational Science Institute, New Orleans, LA, USA.; Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA.; Smith NL; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Seattle Epidemiologic Information and Research Center, Department of Veterans Affairs, Office of Research and Development, Seattle, WA, USA.; Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA.; Schwartz DA; Department of Medicine, University of Colorado, Aurora, CO, USA.; Correa A; Departments of Medicine and Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA.; de Andrade M; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.; Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Konkle BA; Bloodworks Northwest, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Custer B; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA.; Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Gui H; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.; Meyers DA; Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; McGarvey ST; Department of Epidemiology and International Health Institute, Brown University School of Public Health, Providence, RI, USA.; Chen IY; Medical Genetics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Los Angeles, CA, USA.; Shoemaker MB; Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Broome JG; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Wang FF; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Wong Q; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Montasser ME; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Daya M; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA.; Cade BE; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA.; Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Cho MH; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Lasky-Su J; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Cupples LA; Departments of Biostatistics and Epidemiology, Boston University School of Public Health, Boston, MA, USA.; Mak ACY; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.; Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.; Tulane University Translational Science Institute, New Orleans, LA, USA.; Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.; Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Tiwari HK; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA.; Yang IV; Department of Medicine, University of Colorado, Aurora, CO, USA.; Heit JA; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.; Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Johnsen JM; Bloodworks Northwest, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Wenzel SE; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Weeks DE; Departments of Human Genetics and Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Rao DC; Division of Biostatistics, Washington University School of Medicine, St Louis, MO, USA.; Darbar D; Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.; Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.; Tracy RP; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Buth EJ; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Rafaels N; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.; Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Durda P; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Liu Y; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.; Hou L; Department of Preventive Medicine, Northwestern Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Lee J; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Kachroo P; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Freedman BI; Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Levy D; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Hixson JE; Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.; Floyd JS; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Whitsel EA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.; Fingerlin TE; Center for Genes Environment and Health, National Jewish Health, Denver, CO, USA.; Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Armasu SM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.; Wheeler MM; Department of Genome Science, University of Washington, Seattle, WA, USA.; Sabino EC; Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.; Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Williams LK; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.; Levy BD; Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; Manson JE; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.; Mathias RA; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Desai P; Department of Medicine, Weill Cornell Medical School, New York, NY, USA.; Taylor KD; Institute for Translational Genomics and Population Sciences, Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Johnson AD; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Auer PL; Joseph J. Zilber School of Public Health, University of WisconsinMilwaukee, Milwaukee, WI, USA.; Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Blackwell TW; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Smith AV; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Zhao H; Department of Biostatistics, School of Public Health, Yale University, New Haven, CT, USA.; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.; Lange E; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Lange L; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Rotter JI; Institute for Translational Genomics and Population Sciences, Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Scheet P; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Kitzman JO; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Society of Fellows, Harvard University, Cambridge, MA, USA.; Ebert BL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Jaiswal S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Abecasis G; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA.; Sankaran VG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA. sekar@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. sekar@broadinstitute.org.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. sekar@broadinstitute.org.; Verve Therapeutics, Cambridge, MA, USA. sekar@broadinstitute.org.; Natarajan P; Broad Institute of MIT and Harvard, Cambridge, MA, USA. pradeep@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. pradeep@broadinstitute.org.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. pradeep@broadinstitute.org.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE; PubMed not MEDLINE

Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Munschauer M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Anyoha R; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Munson G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Grossman SR; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Division of Health Sciences and Technology, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.; Department of Biology, MIT, Cambridge, MA 02139, USA.; Perez EM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Kane M; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Cleary B; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.; Computational and Systems Biology Program, MIT, Cambridge, MA 02139, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. engreitz@broadinstitute.org lander@broadinstitute.org.; Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.; Department of Biology, MIT, Cambridge, MA 02139, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. engreitz@broadinstitute.org lander@broadinstitute.org.

Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Marshall JL; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Doughty BR; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Subramanian V; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Guckelberger P; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Department of Biology, Chemistry, and Pharmacy, Freie Universität Berlin, 14195 Berlin, Germany.; Wang Q; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114.; Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA 02115.; Chen LM; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Rodriques SG; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139.; MIT Media Lab, Massachusetts Institute of Technology, Cambridge, MA 02139.; Zhang K; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Grinkevich EJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Noel T; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Mangiameli S; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Greka A; Broad Institute of MIT and Harvard, Cambridge, MA 02142.; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA 02142; lander@broadinstitute.org chenf@broadinstitute.org engreitz@stanford.edu.; Department of Systems Biology, Harvard Medical School, Boston, MA 02115.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139.; Chen F; Broad Institute of MIT and Harvard, Cambridge, MA 02142; lander@broadinstitute.org chenf@broadinstitute.org engreitz@stanford.edu.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA 02142; lander@broadinstitute.org chenf@broadinstitute.org engreitz@stanford.edu.; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305.; Basic Science and Engineering Initiative, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Stanford University School of Medicine, Stanford, CA 94305.

Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

Bick AG; Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Weinstock JS; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Nandakumar SK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Bao EL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Health Sciences and Technology Program, Harvard Medical School, Boston, MA, USA.; Zekavat SM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Yale School of Medicine, New Haven, CT, USA.; Szeto MD; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Medical Scientist Training Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Liao X; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Leventhal MJ; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Chang K; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Laurie C; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Burugula BB; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.; Gibson CJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Lin AE; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Taub MA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.; Aguet F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Ardlie K; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA.; Barnes KC; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.; Moscati A; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA.; Redline S; Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Silverman EK; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Weiss ST; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Vasan RS; Departments of Medicine and Epidemiology, Boston University School of Medicine, Boston, MA, USA.; Burchard EG; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, USA.; Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.; Tulane University Translational Science Institute, New Orleans, LA, USA.; Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.; Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, WA, USA.; Smith NL; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Seattle Epidemiologic Information and Research Center, Department of Veterans Affairs, Office of Research and Development, Seattle, WA, USA.; Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA.; Schwartz DA; Department of Medicine, University of Colorado, Aurora, CO, USA.; Correa A; Departments of Medicine and Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA.; de Andrade M; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.; Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.; Konkle BA; Bloodworks Northwest, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Custer B; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA.; Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Gui H; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.; Meyers DA; Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; McGarvey ST; Department of Epidemiology and International Health Institute, Brown University School of Public Health, Providence, RI, USA.; Chen IY; Medical Genetics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Los Angeles, CA, USA.; Shoemaker MB; Division of Cardiology, Vanderbilt University Medical Center, Nashville, TN, USA.; Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Broome JG; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Wang FF; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Wong Q; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Montasser ME; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Daya M; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Kenny EE; Institute for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD, USA.; Cade BE; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Department of Medicine, Harvard Medical School, Boston, MA, USA.; Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Cho MH; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Lasky-Su J; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Cupples LA; Departments of Biostatistics and Epidemiology, Boston University School of Public Health, Boston, MA, USA.; Mak ACY; Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.; Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.; Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.; Tulane University Translational Science Institute, New Orleans, LA, USA.; Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.; Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Tiwari HK; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA.; Yang IV; Department of Medicine, University of Colorado, Aurora, CO, USA.; Heit JA; Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.; Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Johnsen JM; Bloodworks Northwest, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Wenzel SE; Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Weeks DE; Departments of Human Genetics and Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Rao DC; Division of Biostatistics, Washington University School of Medicine, St Louis, MO, USA.; Darbar D; Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.; Moon JY; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, USA.; Tracy RP; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Buth EJ; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Rafaels N; Colorado Center for Personalized Medicine, School of Medicine, University of Colorado, Aurora, CO, USA.; Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Durda P; Department of Pathology and Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, USA.; Liu Y; Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.; Hou L; Department of Preventive Medicine, Northwestern Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.; Lee J; Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Kachroo P; Harvard Medical School, Boston, MA, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Freedman BI; Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Levy D; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Hixson JE; Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, Houston, TX, USA.; Floyd JS; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Medicine, University of Washington, Seattle, WA, USA.; Whitsel EA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.; Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA.; Fingerlin TE; Center for Genes Environment and Health, National Jewish Health, Denver, CO, USA.; Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA.; Armasu SM; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.; Wheeler MM; Department of Genome Science, University of Washington, Seattle, WA, USA.; Sabino EC; Instituto de Medicina Tropical, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.; Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; Williams LK; Center for Individualized and Genomic Medicine Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA.; Levy BD; Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Pharmacology, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Boerwinkle E; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; Manson JE; Harvard Medical School, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.; Mathias RA; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA.; Desai P; Department of Medicine, Weill Cornell Medical School, New York, NY, USA.; Taylor KD; Institute for Translational Genomics and Population Sciences, Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Johnson AD; Framingham Heart Study, Framingham, MA, USA.; Population Sciences Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.; Auer PL; Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.; Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA, USA.; Blackwell TW; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Smith AV; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Zhao H; Department of Biostatistics, School of Public Health, Yale University, New Haven, CT, USA.; Computational Biology and Bioinformatics Program, Yale University, New Haven, CT, USA.; Lange E; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Lange L; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.; Rotter JI; Institute for Translational Genomics and Population Sciences, Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Torrance, CA, USA.; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, USA.; Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Scheet P; Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Kitzman JO; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Society of Fellows, Harvard University, Cambridge, MA, USA.; Ebert BL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Jaiswal S; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Abecasis G; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA.; Sankaran VG; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA. sekar@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. sekar@broadinstitute.org.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA. sekar@broadinstitute.org.; Verve Therapeutics, Cambridge, MA, USA. sekar@broadinstitute.org.; Natarajan P; Broad Institute of MIT and Harvard, Cambridge, MA, USA. pradeep@broadinstitute.org.; Harvard Medical School, Boston, MA, USA. pradeep@broadinstitute.org.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA. pradeep@broadinstitute.org.

Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Nasser J; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Jones TR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Munson G; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Bergman DT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Subramanian V; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Grossman SR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Biology, MIT, Cambridge, MA, USA.; Anyoha R; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Doughty BR; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Patwardhan TA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Nguyen TH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Kane M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Perez EM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Durand NC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Department of Computer Science and Department of Computational and Applied Mathematics, Rice University, Houston, TX, USA.; Lareau CA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Stamenova EK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Aiden EL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; The Center for Genome Architecture, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Department of Computer Science and Department of Computational and Applied Mathematics, Rice University, Houston, TX, USA.; Center for Theoretical Biological Physics, Rice University, Houston, TX, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA. lander@broadinstitute.org.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA. lander@broadinstitute.org.; Department of Biology, MIT, Cambridge, MA, USA. lander@broadinstitute.org.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA. engreitz@broadinstitute.org.; Harvard Society of Fellows, Harvard University, Cambridge, MA, USA. engreitz@broadinstitute.org.

Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

Hsu JY; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Fulco CP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Cole MA; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Canver MC; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Pellin D; Gene Therapy Program, Harvard Medical School, Boston, MA, USA.; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; Sher F; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Farouni R; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Clement K; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Guo JA; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Biasco L; Gene Therapy Program, Harvard Medical School, Boston, MA, USA.; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, MA, USA.; Orkin SH; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.; Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA.; Engreitz JM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Society of Fellows, Harvard University, Cambridge, MA, USA.; Lander ES; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Systems Biology, Harvard Medical School, Boston, MA, USA.; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.; Joung JK; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA.; Department of Pathology, Harvard Medical School, Boston, MA, USA.; Bauer DE; Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA. bauer@bloodgroup.tch.harvard.edu.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. bauer@bloodgroup.tch.harvard.edu.; Harvard Stem Cell Institute, Department of Pediatrics, Harvard Medical School, Boston, MA, USA. bauer@bloodgroup.tch.harvard.edu.; Pinello L; Molecular Pathology Unit, Center for Cancer Research, Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA. lpinello@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. lpinello@mgh.harvard.edu.; Department of Pathology, Harvard Medical School, Boston, MA, USA. lpinello@mgh.harvard.edu.

Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE