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발행년	- (예 : 2010-2015)

C5-Alkyl-2-methylurea-substituted pyridines as a new class of glucokinase activators

Academic Journal

Du, X.; Xiong, Y.; Dransfield, P.; Park, J.; Kohn, T.J.; Pattaropong, V.; Lai, S.; Fu, Z.; Jiao, X.; Chow, D.; Jin, L.; Davda, J.; Conn, M.; Tran, T.; Yang, J.; Medina, J.C.; Coward, P.; Houze, J.B.; Veniant, M.M.; Hinklin, R.J.; Anderson, D.A.; Baer, B.R.; Bencsik, J.R.; Boyd, S.A.; Chicarelli, M.J.; Mohr, P.J.; Wang, B.; Condroski, K.R.; Dewolf, W.E.; Aicher, T.D.

In: ACS Medicinal Chemistry Letters. (ACS Medicinal Chemistry Letters, 11 December 2014, 5(12):1284-1289)

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Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumors

Academic Journal

Blake, J.F.; Xu, R.; Bencsik, J.R.; Xiao, D.; Kallan, N.C.; Schlachter, S.; Mitchell, I.S.; Spencer, K.L.; Banka, A.L.; Wallace, E.M.; Gloor, S.L.; Martinson, M.; Woessner, R.D.; Vigers, G.P.A.; Brandhuber, B.J.; Liang, J.; Safina, B.S.; Li, J.; Zhang, B.; Chabot, C.; Do, S.; Lee, L.; Oeh, J.; Sampath, D.; Lee, B.B.; Lin, K.; Liederer, B.M.; Skelton, N.J.

In: Journal of Medicinal Chemistry. (Journal of Medicinal Chemistry, 27 September 2012, 55(18):8110-8127)

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Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA

Academic Journal

Xu, R.; Banka, A.; Blake, J.F.; Mitchell, I.S.; Wallace, E.M.; Bencsik, J.R.; Kallan, N.C.; Spencer, K.L.; Gloor, S.L.; Martinson, M.; Risom, T.; Gross, S.D.; Morales, T.H.; Wu, W.-I.; Vigers, G.P.A.; Brandhuber, B.J.; Skelton, N.J.

In: Bioorganic and Medicinal Chemistry Letters. (Bioorganic and Medicinal Chemistry Letters, 15 April 2011, 21(8):2335-2340)

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Discovery and SAR of spirochromane Akt inhibitors

Academic Journal

Kallan, N.C.; Spencer, K.L.; Blake, J.F.; Xu, R.; Heizer, J.; Bencsik, J.R.; Mitchell, I.S.; Gloor, S.L.; Martinson, M.; Risom, T.; Gross, S.D.; Morales, T.H.; Wu, W.-I.; Vigers, G.P.A.; Brandhuber, B.J.; Skelton, N.J.

In: Bioorganic and Medicinal Chemistry Letters. (Bioorganic and Medicinal Chemistry Letters, 15 April 2011, 21(8):2410-2414)

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Discovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors

Academic Journal

Bencsik, J.R.; Xiao, D.; Blake, J.F.; Kallan, N.C.; Mitchell, I.S.; Spencer, K.L.; Xu, R.; Gloor, S.L.; Martinson, M.; Risom, T.; Woessner, R.D.; Dizon, F.; Wu, W.-I.; Vigers, G.P.A.; Brandhuber, B.J.; Skelton, N.J.; Prior, W.W.; Murray, L.J.

In: Bioorganic and Medicinal Chemistry Letters. (Bioorganic and Medicinal Chemistry Letters, 1 December 2010, 20(23):7037-7041)

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Discovery of pyrrolopyrimidine inhibitors of Akt

Academic Journal

Blake, J.F.; Kallan, N.C.; Xiao, D.; Xu, R.; Bencsik, J.R.; Spencer, K.L.; Mitchell, I.S.; Woessner, R.D.; Gloor, S.L.; Risom, T.; Gross, S.D.; Martinson, M.; Morales, T.H.; Vigers, G.P.A.; Brandhuber, B.J.; Skelton, N.J.

In: Bioorganic and Medicinal Chemistry Letters. (Bioorganic and Medicinal Chemistry Letters, 1 October 2010, 20(19):5607-5612)

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Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: Efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles

Academic Journal

Kercher, T.; Rao, C.; Bencsik, J.R.; Josey, J.A.

In: Journal of Combinatorial Chemistry. (Journal of Combinatorial Chemistry, November 2007, 9(6):1177-1187)

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Efficient, stereoselective synthesis of oxazolo[3,2-a]pyrazin-5-ones: Novel bicyclic lactam scaffolds from the bicyclocondensation of 3-aza-1,5-ketoacids and amino alcohols

Academic Journal

Bencsik, J.R.; Kercher, T.; O'Sullivan, M.; Josey, J.A.

In: Organic Letters. (Organic Letters, 24 July 2003, 5(15):2727-2730)

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Enantioselective synthesis of (-)-LL-C10037α from benzoquinone

Academic Journal

Murphy, S.T.; Bencsik, J.R.; Johnson, C.R.

In: Organic Letters. (Organic Letters, 4 November 1999, 1(9):1483-1485)

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