학술논문
Global burden of peripheral artery disease and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
Document Type
Author
Kim, Min Seo; Hwang, Jimin; Yon, Dong Keon; Lee, Seung Won; Jung, Se Yong; Park, Seoyeon; Johnson, Catherine Owens; Stark, Benjamin A.; Razo, Christian; Abbasian, Mohammadreza; Abbastabar, Hedayat; Abhari, Amir Parsa; Aboyans, Victor; Adane, Denberu Eshetie Adane; Adebayo, Oladimeji M.; Alahdab, Fares; Almustanyir, Sami; Aly, Hany; Ameyaw, Edward Kwabena; Anderson, Jason A.; Andrei, Catalina Liliana; Aryan, Zahra; Aujayeb, Avinash; Bagherieh, Sara; Baltatu, Ovidiu Constantin; Banach, Maciej; Bayileyegn, Nebiyou Simegnew; Bearne, Lindsay M.; Behnoush, Amir Hossein; Bensenor, Isabela M.; Bhaskar, Sonu; Bhat, Ajay Nagesh; Bhat, Vivek; Bikbov, Boris; Bintoro, Bagas Suryo; Burkart, Katrin; Camera, Luis Alberto; Catapano, Alberico L.; Chandrasekar, Eeshwar K.; Charan, Jaykaran; Chattu, Vijay Kumar; Chi, Gerald; Chukwu, Isaac Sunday; Chung, Sheng-Chia; Cirillo, Massimo; Coberly, Kaleb; Costa, Vera Marisa; Dadras, Omid; Dai, Xiaochen; Do, Thanh Chi; Doshi, Rajkumar; Ekholuenetale, Michael; Elgendy, Islam Y.; Elhadi, Muhammed; Fagbamigbe, Adeniyi Francis; Feizkhah, Alireza; Fekadu, Ginenus; Gill, Paramjit Singh; Goldust, Mohamad; Golechha, Mahaveer; Guan, Shi-Yang; Gupta, Vivek Kumar; Hadei, Mostafa; Hadi, Najah R.; Hammoud, Ahmad; Hankey, Graeme J.; Harlianto, Netanja, I; Hasaballah, Ahmed, I; Hassan, Shoaib; Hassen, Mohammed Bheser; Heidari, Golnaz; Hostiuc, Mihaela; Ilesanmi, Olayinka Stephen; Iwagami, Masao; Jokar, Mohammad; Jonas, Jost B.; Joshua, Charity Ehimwenma; Jozwiak, Jacek Jerzy; Kazemian, Sina; Keykhaei, Mohammad; Khalaji, Amirmohammad; Khan, Moien A. B.; Khateri, Sorour; Kibret, Biruk Getahun; Korzh, Oleksii; Laxminarayana, Sindhura Lakshmi Koulmane; Krishan, Kewal; Kumar, Akshay; Kumar, Manoj; Kuttikkattu, Ambily; Laksono, Tri; Larijani, Bagher; Le, Thao Thi Thu; Lim, Stephen S.; Liu, Xuefeng; Lorkowski, Stefan; Abd El Razek, Hassan Magdy; Malhotra, Kashish; Manla, Yosef; Maugeri, Andrea; Mentis, Alexios-Fotios A.; Mestrovic, Tomislav; de Sa, Ana Carolina Micheletti Gomide Nogueira; Mirica, Andreea; Mirrakhimov, Erkin M.; Misganaw, Awoke; Mishra, Manish; Mohammad, Yousef; Mokdad, Ali H.; Moni, Mohammad Ali; Al Montasir, Ahmed; Moradi, Yousef; Moraga, Paula; Morovatdar, Negar; Mousavi-Aghdas, Seyed Ali; Murray, Christopher J. L.; Naghavi, Mohsen; Nair, Tapas Sadasivan; Nassereldine, Hasan; Natto, Zuhair S.; Nguyen, Dang H.; Nguyen, Hien Quang; Nguyen, Van Thanh; Noubiap, Jean Jacques; Oancea, Bogdan; Oliveira, Glaucia Maria Moraes; Owolabi, Mayowa O.; Padron-Monedero, Alicia; Perico, Norberto; Petcu, Ionela-Roxana; Radfar, Amir; Rafferty, Quinn; Rahman, Mosiur; Rahman, Muhammad Aziz; Ram, Pradhum; Rashedi, Sina; Rashid, Ahmed Mustafa; Rawaf, Salman; Remuzzi, Giuseppe; Renzaho, Andre M. N.; Rezaee, Malihe; Roever, Leonardo; Saad, Aly M. A.; Saadatagah, Seyedmohammad; Sadeghi, Masoumeh; Sahebkar, Amirhossein; Saleh, Mohamed A.; Samy, Abdallah M.; Santric-Milicevic, Milena M.; Sepanlou, Sadaf G.; Seylani, Allen; Sharfaei, Sadaf; Shorofi, Seyed Afshin; Singh, Jasvinder A.; Singh, Paramdeep; Spartalis, Michael; Sundström, Johan, Professor, 1971; Tan, Ker-Kan; Teramoto, Masayuki; Tharwat, Samar; Tyrovolas, Stefanos; Tahbaz, Sahel Valadan; Van den Eynde, Jef; Vart, Priya; Wang, Cong; Wang, Fang; Westerman, Ronny; Xia, Juan; Xu, Suowen; Yada, Dereje Y.; Yamagishi, Kazumasa; Yonemoto, Naohiro; Zahir, Mazyar; Zangiabadian, Moein; Zarrintan, Armin; Zastrozhin, Mikhail Sergeevich; Zastrozhina, Anasthasia; Zoladl, Mohammad; Hay, Simon, I; Shin, Jae Il; Roth, Gregory A.
Source
The Lancet Global Health. 11(10):E1553-E1565
Subject
Language
English
ISSN
2214-109X
Abstract
Background: Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures.Methods: Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed.Findings: In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95% uncertainty interval [UI] 99 center dot 2-128 center dot 4), with a global prevalence of 1 center dot 52% (95% UI 1 center dot 33-1 center dot 72), of which 42 center dot 6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14 center dot 91% [12 center dot 41-17 center dot 87] in those aged 80-84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69 center dot 4% (64 center dot 2-74 center dot 3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles.Interpretation: The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors.