학술논문

Priorities in Cardio-Oncology Basic and Translational Science : GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review
Document Type
Source
JACC: CardioOncology EXODIAB: Excellence of Diabetes Research in Sweden. 5(6):715-731
Subject
anthracyclines
basic research
cancer
cardiac arrhythmias
cardio-oncology
cardiotoxicity
chemotherapy
immunotherapy
translational research
Medicin och hälsovetenskap
Klinisk medicin
Kardiologi
Medical and Health Sciences
Clinical Medicine
Cardiac and Cardiovascular Systems
Language
English
ISSN
2666-0873
Abstract
Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care. We acknowledge that there are many additional therapies that are of significance but were not topics of discussion at this symposium. We hope that through this symposium-based review we can highlight the knowledge gaps and clinical priorities to inform the design of future studies that aim to prevent and mitigate cardiovascular disease in cancer patients and survivors.