학술논문

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.
Document Type
Author
Jansen, Willemijn JOssenkoppele, RikKnol, Dirk LTijms, Betty MScheltens, PhilipVerhey, Frans R JVisser, Pieter JelleAalten, PaulineAarsland, DagAlcolea, DanielAlexander, MyriamAlmdahl, Ina SArnold, Steven EBaldeiras, InêsBarthel, Henrykvan Berckel, Bart N MBibeau, KristenBlennow, KajBrooks, David Jvan Buchem, Mark ACamus, VincentCavedo, EnricaChen, KeweiChetelat, GaelCohen, Ann DDrzezga, AlexanderEngelborghs, SebastiaanFagan, Anne MFladby, TormodFleisher, Adam Svan der Flier, Wiesje MFord, LisaFörster, StefanFortea, JuanFoskett, NadiaFrederiksen, Kristian SFreund-Levi, YvonneFrisoni, Giovanni BFroelich, LutzGabryelewicz, TomaszGill, Kiran DipGkatzima, OlymbiaGómez-Tortosa, EstrellaGordon, Mark ForrestGrimmer, TimoHampel, HaraldHausner, LucreziaHellwig, SabineHerukka, Sanna-KaisaHildebrandt, HelmutIshihara, LiannaIvanoiu, AdrianJagust, William JJohannsen, PeterKandimalla, RameshKapaki, ElisabethKlimkowicz-Mrowiec, AleksandraKlunk, William EKöhler, SebastianKoglin, NormanKornhuber, JohannesKramberger, Milica GVan Laere, KoenLandau, Susan MLee, Dong Youngde Leon, MonyLisetti, VivianaLleó, AlbertoMadsen, KarineMaier, WolfgangMarcusson, JanMattsson, Niklasde Mendonça, AlexandreMeulenbroek, OlgaMeyer, Philipp TMintun, Mark AMok, VincentMolinuevo, José LuisMøllergård, Hanne MMorris, John CMroczko, BarbaraVan der Mussele, StefanNa, Duk LNewberg, AndrewNordberg, AgnetaNordlund, ArtoNovak, Gerald PParaskevas, George PParnetti, LucillaPerera, GayanPeters, OliverPopp, JuliusPrabhakar, SudeshRabinovici, Gil DRamakers, Inez H G BRami, LorenaResende de Oliveira, CatarinaRinne, Juha ORodrigue, Karen MRodríguez-Rodríguez, EloyRoe, Catherine MRot, UrosRowe, Christopher CRüther, EckartSabri, OsamaSanchez-Juan, PáscualSantana, IsabelSarazin, MarieSchröder, JohannesSchütte, ChristinSeo, Sang WSoetewey, FemkeSoininen, HilkkaSpiru, LuizaStruyfs, HanneTeunissen, Charlotte ETsolaki, MagdaVandenberghe, RikVerbeek, Marcel MVillemagne, Victor LVos, Stephanie J Bvan Waalwijk van Doorn, Linda J CWaldemar, GunhildWallin, AndersWallin, ÅsaWiltfang, JensWolk, David AZboch, MarzenaZetterberg, Henrik
Source
JAMA: The Journal of the American Medical Association MultiPark: Multidisciplinary research focused on Parkinson´s disease. 313(19):1924-1938
Subject
Amyloid beta-Peptides: analysis
Apolipoprotein E4: genetics
Biological Markers: analysis
Brain: pathology
Cerebrospinal Fluid: chemistry
Dementia: pathology
Mild Cognitive Impairment: pathology
Medicin och hälsovetenskap
Klinisk medicin
Neurologi
Medical and Health Sciences
Clinical Medicine
Neurology
Language
English
ISSN
1538-3598
Abstract
Cerebral amyloid-β aggregation is an early pathological event in Alzheimer disease (AD), starting decades before dementia onset. Estimates of the prevalence of amyloid pathology in persons without dementia are needed to understand the development of AD and to design prevention studies.