학술논문

Associations of sedentary time, physical activity, and fitness with muscle glucose uptake in adults with metabolic syndrome
Document Type
Source
Scandinavian Journal of Medicine and Science in Sports. 33(3):353-358
Subject
insulin resistance
physical activity
positron emission tomography
sedentary behavior
skeletal muscle
Language
English
ISSN
0905-7188
1600-0838
Abstract
Objective: The objective of the study was to investigate the associations of sedentary time, physical activity, and cardiorespiratory fitness with skeletal muscle glucose uptake (GU). Methods: Sedentary time and physical activity were measured with accelerometers and VO2max with cycle ergometry in 44 sedentary adults with metabolic syndrome. Thigh muscle GU was determined with [18F]FDG-PET imaging. Results: Sedentary time (β = −0.374), standing (β = 0.376), steps (β = 0.351), and VO2max (β = 0.598) were associated with muscle GU when adjusted for sex, age, and accelerometer wear time. Adjustment for body fat-% turned all associations non-significant. Conclusion: Body composition is a more important determinant of muscle GU in this population than sedentary time, physical activity, or fitness. © 2022 The Authors. Scandinavian Journal of Medicine & Science In Sports published by John Wiley & Sons Ltd.