학술논문

Improved resolution in x-ray tomography by super-resolution
Document Type
Source
Applied Optics. 60(20):5783-5794
Subject
Medicin och hälsovetenskap
Klinisk medicin
Radiologi och bildbehandling
Medical and Health Sciences
Clinical Medicine
Radiology
Nuclear Medicine and Medical Imaging
Naturvetenskap
Fysik
Annan fysik
Natural Sciences
Physical Sciences
Other Physics Topics
Language
English
ISSN
2155-3165
Abstract
In this paper, super-resolution imaging is described and evaluated for x-ray tomography and is compared with standard tomography and upscaling during reconstruction. Blurring is minimized due to the negligible point spread of photon counting detectors and an electromagnetically movable micro-focus x-ray spot. Scans are acquired in high and lowmagnification geometry, where the latter is used to minimize penumbral blurring fromthe x-ray source. Sharpness and level ofdetail can be significantly increased in reconstructed slices to the point where the source size becomes the limiting factor. The achieved resolution of the different methods is quantified and compared using biological samples via the edge spread function, modulation transfer function, and Fourier ring correlation.