학술논문
The european hematology association roadmap for european hematology research : A consensus document
Document Type
Author
Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; De Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; De Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Sall Es, Gilles; Schuringa, Jan Jacob; André, Marc; Andre-Schmutz, Isabelle; Bacigalupo, Andrea; Bochud, Pierre Yves; Den Boer, Monique; Bonini, Chiara; Camaschella, Clara; Cant, Andrew; Cappellini, Maria Domenica; Cazzola, Mario; Celso, Cristina Lo; Dimopoulos, Meletios; Douay, Luc; Dzierzak, Elaine; Einsele, Hermann; Ferreri, Andrés; De Franceschi, Lucia; Gaulard, Philippe; Gottgens, Berthold; Greinacher, Andreas; Gresele, Paolo; Gribben, John; De Haan, Gerald; Hansen, John Bjarne; Hochhaus, Andreas; Kadir, Rezan; Kaveri, Srini; Kouskoff, Valerie; Kühne, Thomas; Kyrle, Paul; Ljungman, Per; Maschmeyer, Georg; Méndez-Ferrer, Simón; Milsom, Michael; Mummery, Christine; Ossenkoppele, Gert; Pecci, Alessandro; Peyvandi, Flora; Philipsen, Sjaak; Reitsma, Pieter; Ribera, José Maria; Risitano, Antonio; Rivella, Stefano; Ruf, Wolfram; Schroeder, Timm; Scully, Marie; Socie, Gerard; Staal, Frank; Stanworth, Simon; Stauder, Reinhard; Stilgenbauer, Stephan; Tamary, Hannah; Theilgaard-Mönch, Kim; Thein, Swee Lay; Tilly, Hervé; Trneny, Marek; Vainchenker, William; Vannucchi, Alessandro Maria; Viscoli, Claudio; Vrielink, Hans; Zaaijer, Hans; Zanella, Alberto; Zolla, Lello; Zwaginga, Jaap Jan; Martinez, Patricia Aguilar; Van Den Akker, Emile; Allard, Shubha; Anagnou, Nicholas; Andolfo, Immacolata; Andrau, Jean Christophe; Angelucci, Emanuele; Anstee, David; Aurer, Igor; Avet-Loiseau, Hervé; Aydinok, Yesim; Bakchoul, Tamam; Balduini, Alessandra; Barcellini, Wilma; Baruch, Dominique; Baruchel, André; Bayry, Jagadeesh; Bento, Celeste; Van Den Berg, Anke; Bernardi, Rosa; Bianchi, Paola; Bigas, Anna; Biondi, Andrea; Bohonek, Milos; Bonnet, Dominique; Borchmann, Peter; Borregaard, Niels; Brækkan, Sigrid; Van Den Brink, Marcel; Brodin, Ellen; Bullinger, Lars; Buske, Christian; Butzeck, Barbara; Cammenga, Jörg; Campo, Elias; Carbone, Antonino; Cervantes, Francisco; Cesaro, Simone; Charbord, Pierre; Claas, Frans; Cohen, Hannah; Conard, Jacqueline; Coppo, Paul; Vives Corron, Joan Lluis; Da Costa, Lydie; Davi, Frederic; Delwel, Ruud; Dianzani, Irma; Domanović, Dragoslav; Donnelly, Peter; Drnovšek, Tadeja Dovč; Dreyling, Martin; Du, Ming Qing; Dufour, Carlo; Durand, Charles; Efremov, Dimitar; Eleftheriou, Androulla; Elion, Jacques; Emonts, Marieke; Engelhardt, Monika; Ezine, Sophie; Falkenburg, Fred; Favier, Remi; Federico, Massimo; Fenaux, Pierre; Fitzgibbon, Jude; Flygare, Johan; Foà, Robin; Forrester, Lesley; Galacteros, Frederic; Garagiola, Isabella; Gardiner, Chris; Garraud, Olivier; Van Geet, Christel; Geiger, Hartmut; Geissler, Jan; Germing, Ulrich; Ghevaert, Cedric; Girelli, Domenico; Godeau, Bertrand; Gökbuget, Nicola; Goldschmidt, Hartmut; Goodeve, Anne; Graf, Thomas; Graziadei, Giovanna; Griesshammer, Martin; Gruel, Yves; Guilhot, Francois; Von Gunten, Stephan; Gyssens, Inge; Halter, Jörg; Harrison, Claire; Harteveld, Cornelis; Hellström-Lindberg, Eva; Hermine, Olivier; Higgs, Douglas; Hillmen, Peter; Hirsch, Hans; Hoskin, Peter; Huls, Gerwin; Inati, Adlette; Johnson, Peter; Kattamis, Antonis; Kiefel, Volker; Kleanthous, Marina; Klump, Hannes; Krause, Daniela; Hovinga, Johanna Kremer; Lacaud, Georges; Lacroix-Desmazes, Sébastien; Landman-Parker, Judith; Legouill, Steven; Lenz, Georg; Von Lilienfeld-Toal, Marie; Von Lindern, Marieke; Lopez-Guillermo, Armando; Lopriore, Enrico; Lozano, Miguel; Macintyre, Elizabeth; Makris, Michael; Mannhalter, Christine; Martens, Joost; Mathas, Stephan; Matzdorff, Axel; Medvinsky, Alexander; Menendez, Pablo; Migliaccio, Anna Rita; Miharada, Kenichi; Mikulska, Malgorzata; Minard, Véronique; Montalbán, Carlos; De Montalembert, Mariane; Montserrat, Emili; Morange, Pierre Emmanuel; Mountford, Joanne; Muckenthaler, Martina; Müller-Tidow, Carsten; Mumford, Andrew; Nadel, Bertrand; Navarro, Jose Tomas; El Nemer, Wassim; Noizat-Pirenne, France; O’Mahony, Brian; Oldenburg, Johannes; Olsson, Martin; Oostendorp, Robert; Palumbo, Antonio; Passamonti, Francesco; Patient, Roger; De Latour, Regis Peffault; Pflumio, Francoise; Pierelli, Luca; Piga, Antonio; Pollard, Debra; Raaijmakers, Marc; Radford, John; Rambach, Ralf; Koneti Rao, A.; Raslova, Hana; Rebulla, Paolo; Rees, David; Ribrag, Vincent; Rijneveld, Anita; Rinalducci, Sara; Robak, Tadeusz; Roberts, Irene; Rodrigues, Charlene; Rosendaal, Frits; Rosenwald, Andreas; Rule, Simon; Russo, Roberta; Saglio, Guiseppe; Sanchez, Mayka; Scharf, Rüdiger E.; Schlenke, Peter; Semple, John; Sierra, Jorge; So-Osman, Cynthia; Soria, José Manuel; Stamatopoulos, Kostas; Stegmayr, Bernd; Stunnenberg, Henk; Swinkels, Dorine; Barata, João Pedro Taborda; Taghon, Tom; Taher, Ali; Terpos, Evangelos; Thachil, Jecko; Tissot, Jean Daniel; Touw, Ivo; Toye, Ash; Trappe, Ralf; Traverse-Glehen, Alexandra; Unal, Sule; Vaulont, Sophie; Viprakasit, Vip; Vitolo, Umberto; Van Wijk, Richard; Wójtowicz, Agnieszka; Zeerleder, Sacha; Zieger, Barbara
Source
Haematologica BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation StemTherapy: National Initiative on Stem Cells for Regenerative Therapy EpiHealth: Epidemiology for Health. 101(2):115-208
Subject
Language
English
ISSN
0390-6078
Abstract
The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at ∈ European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better fu treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap. The EHA Roadmap identifies nine ‘sections’ in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders. The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.