학술논문

Response of pig skin to single and fractionated high dose-rate and continuous low dose-rate /sup 137/Cs-irradiation. II. Theoretical considerations of the results
Document Type
Journal Article
Author
Source
Int. J. Radiat. Oncol., Biol. Phys.; (United States); 5:7
Subject
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT. DOSE RATES
RADIOSENSITIVITY EFFECTS
RADIATION DOSES
SKIN
BIOLOGICAL RADIATION EFFECTS
SWINE
CESIUM 137
CHRONIC IRRADIATION
COMPARATIVE EVALUATIONS
DATA COMPILATION
DOSE-RESPONSE RELATIONSHIPS
EXPERIMENTAL DATA
FRACTIONATED IRRADIATION
LOW DOSE IRRADIATION
OXYGEN ENHANCEMENT RATIO
ALKALI METAL ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
CESIUM ISOTOPES
CHRONIC EXPOSURE
DATA
DOMESTIC ANIMALS
DOSES
INFORMATION
IRRADIATION
ISOTOPES
MAMMALS
NUCLEI
NUMERICAL DATA
ODD-EVEN NUCLEI
ORGANS
RADIATION EFFECTS
RADIOISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES 550603* -- Medicine-- External Radiation in Therapy-- (1980-)
560152 -- Radiation Effects on Animals-- Animals
Language
English
Abstract
The result of a comparison of single and fractionated irradiation at high dose rate with continuous irradiation at low dose rate on pig skin is discussed from a radiobiological point of view. A short review is given of other fractionation and dose-rate investigations. Some dose-rate experiments have resulted in an increased therapeutic gain for continuous irradiation at low dose rate, compared to single acute irradiation. However, there is a lack of data comparing fractionated high dose-rate irradiation with continuous low dose-rate irradiation on normal tissues as well as malignant tumors.