부산대학교 도서관

From animal experimental studies and observations on irradiated patients, a subdivision of the irradiation consequences into three groups was made, which considered the clinically establishable different results as a result of the irradiation dose. Irradiation hypertonia which was interpreted as renal hypertonia was the first subdivision. It occurs after irradiation of one or both kidneys with doses from 500 to 2000 r. The injuries to the renal tissue, which are slight and partially reversible, first occur after hypertonia. The second subdivision is irradiation nephritis, in which after irradiation of the whole kidney tissue with average doses of 2300 r (up to 3000 r) a hypertonia and a heavy radiation injury to the kidney parenchyma occurs. The course of the sickness was determined by the combination of hypertonia and kidney damage. Irradiation fibrosis or cirrhosis (the third subdivision) is indicated by a severe, irreversible, and progressive radiation damage of the kidney parenchyma with lethal results in uremia. Hypertonia was not present or has at least no pathogenetic significance. (tr-auth)