학술논문

Effects of acute low-level microwaves on pentobarbital-induced hypothermia depend on exposure orientation
Document Type
Journal Article
Author
Source
Bioelectromagnetics (N.Y.); (United States); 5:2
Subject
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT. MICROWAVE RADIATION
BIOLOGICAL EFFECTS
HYPOTHERMIA
PHENOBARBITAL
RATS
ANESTHETICS
ANIMALS
ANTICONVULSANTS
AZINES
BARBITURATES
BODY TEMPERATURE
CENTRAL NERVOUS SYSTEM DEPRESSANTS
DRUGS
ELECTROMAGNETIC RADIATION
HETEROCYCLIC COMPOUNDS
HYPNOTICS AND SEDATIVES
MAMMALS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANIC OXYGEN COMPOUNDS
PYRIMIDINES
RADIATIONS
RODENTS
VERTEBRATES 560400* -- Other Environmental Pollutant Effects
560205 -- Thermal Effects-- Vertebrates-- (-1987)
Language
English
Abstract
Two series of experiments were performed to study the effects of acute exposure (45 min) to 2,450-MHz circularly polarized, pulsed microwaves (1 mW/cm2, 2-mus pulses, 500 pps, specific absorption rate (SAR) 0.6 W/kg) on the actions of pentobarbital in the rat. In the first experiment, rats were irradiated with microwaves and then immediately injected with pentobarbital. Microwave exposure did not significantly affect the extent of the pentobarbital-induced fall in colonic temperature. However, the rate of recovery from the hypothermia was significantly slower in the microwave-irradiated rats and they also took a significantly longer time to regain their righting reflex. In a second experiment, rats were first anesthetized with pentobarbital and then exposed to microwaves with their heads either pointing toward the source of microwaves (anterior exposure) or pointing away (posterior exposure). Microwave radiation significantly retarded the pentobarbital-induced fall in colonic temperature regardless of the orientation of exposure. However, the recovery from hypothermia was significantly faster in posterior-exposed animals compared to those of the anterior-exposed and sham-irradiated animals. Furthermore, the posterior-exposed rats took a significantly shorter time to regain their righting reflex than both the anterior-exposed and sham-irradiated animals.