학술논문

Immunologic disturbances can explain chronic fatigue syndrome. Biological findings point towards somatogenesis / Immunstörningar kan förklara kroniskt trötthetssyndrom. Biologiska fynd pekar på somatogenes
Document Type
Review
Översikt
Source
Läkartidningen. 106(36):2209
Subject
Diagnosis, Differential / Differentialdiagnostik
Humans / Människa
Life Change Events / Livsavgörande händelser
Patient Care Planning / Vårdplanering
Psychophysiologic Disorders -- etiology -- immunology / Psykosomatiska sjukdomar -- sjukdomsorsak -- immunologi
Risk Factors / Riskfaktorer
Fatigue Syndrome, Chronic -- immunology -- psychology -- diagnosis -- etiology / Trötthetssyndrom, kroniskt -- immunologi -- psykologi -- diagnos -- sjukdomsorsak
Comorbidity / Komorbiditet
Disease Progression / Sjukdomsförlopp
Language
Swedish
ISSN
0023-7205
Abstract
Myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS) are syndromes that are brought together to one disorder with diagnose number G93.3. ME/CFS comprises a range of symptoms of which chronic disabling fatigue is dominant. There may be a number of triggering factors present such as an acute infection and or significant life events. A variation of the severity of symptoms is to be expected as a part of ME/CFS. Setbacks may be triggered by unplanned activities, poor sleep, infection or stress. The patients exhibit post-exertional malaise in response to minimal efforts. The etiology is unknown and there is no known pharmacological treatment or cure for ME/CFS. Symptoms should be managed as in usual clinical practice. The disorder can cause profound, prolonged illness and disability. Co-existing conditions are fibromyalgia, irritable bowel syndrome and depression.