학술논문
Skip to the end: metastasis before tumorigenesis
Document Type
Brief Communication
Author
Source
Nature Genetics. 54(12):1774-1775
Subject
Language
English
ISSN
1061-4036
1546-1718
1546-1718
Abstract
Mutations in the sodium channel NALCN promote epithelial cell shedding and dissemination independent of oncogenic transformation. This observation suggests that metastasis may not uniformly represent the end stage of carcinogenesis but can occur before oncogenic transformation.