부산대학교 도서관

Purpose: To verify whether percentage of body fat, physical fitness, physical activity and calorie intake mediates the multicomponent intervention effect on cardiometabolic risk factors in overweight/obese children, and present the relative contribution of each mediator.Methods: This is an intervention study, developed with 35 overweight/obese school-aged children (control group = 17 and intervention group = 18), aged between 7 and 13 years (9.05 ± 1.90). A 12-week multicomponent intervention was performed, consisting of physical exercise, nutritional education sessions and parental support. The following variables were evaluated at baseline and post-intervention: anthropometric measures and percentage of body fat, physical fitness, physical activity assessed by accelerometer, total calorie intake and biochemical assays. For statistical analysis, generalized linear models were used.Results: The intervention effect on glucose was mediated by percentage of body fat (24%), muscular fitness (22%) and total calorie intake (40%). The same was observed for alanine aminotransferase (ALT), with a mediation proportion of 26, 31 and 35%, respectively, as well as for HDL-C (percentage of body fat − 30%, muscular fitness − 30% and total calorie intake − 33%); while vigorous physical activity mediated the intervention effect on glucose (40%), HDL-C (39%) LDL-C (43%) and total cholesterol (37%).Conclusion: Interventions strategies should focus on reducing percentage of body fat and calorie intake, and enhancing muscular fitness and vigorous physical activity to achieve effective changes on cardiometabolic risk factors.