학술논문

Proliferative vitreoretinopathy: an update on the current and emerging treatment options
Document Type
Review Paper
Source
Graefe's Archive for Clinical and Experimental Ophthalmology: Incorporating German Journal of Ophthalmology. 262(3):679-687
Subject
PVR
Proliferative vitreoretinopathy
Vitrectomy
Steroids
Methotrexate
Language
English
ISSN
0721-832X
1435-702X
Abstract
Proliferative vitreoretinopathy (PVR) remains the main cause of failure in retinal detachment (RD) surgery and a demanding challenge for vitreoretinal surgeons. Despite the large improvements in surgical techniques and a better understanding of PVR pathogenesis in the last years, satisfactory anatomical and visual outcomes have not been provided yet. For this reason, several different adjunctive pharmacological agents have been investigated in combination with surgery. In this review, we analyze the current and emerging adjunctive treatment options for the management of PVR and we discuss their possible clinical application and beneficial role in this subgroup of patients.