학술논문

Reactive oxygen species in the process of labor
Document Type
Original Paper
Source
Archives of Gynecology and Obstetrics. December 1999 263(1-2):23-24
Subject
Key words Reactive oxygen species
Lipid peroxidation
Prostaglandin
Initiation of labor
Umbilical cord blood
Language
English
ISSN
0932-0067
1432-0711
Abstract
Abstract :Levels of thiobarbituric acid reactive substances (TBARS), an indicative parameter for oxidative damage, were measured in maternal and cord arterial and venous bloods, and compared between abdominal and vaginal deliveries. Spontaneous labor resulting in either vaginal or emergency abdominal deliveries was associated with a statistically significant higher levels of TBARS in cord artery compared to cord vein and maternal blood (p<0.05). The results support a role of reactive oxygen species in the initiation of labor, possibly through their effect on prostaglandin metabolism. Alternatively, this may be a marker of fetal oxidative stress, secondary to the process of labor.