학술논문
Clinical impact of Prostate-Specific Membrane Antigen Positron Emission Tomography (PET) on intensification or deintensification of advanced renal cell carcinoma management
Document Type
Original Paper
Author
Pathmanathan, Shivanshan; Tariq, Arsalan; Pearce, Adam; Rhee, Handoo; Kyle, Samuel; Raveenthiran, Sheliyan; Wong, David; McBean, Rhiannon; Marsh, Phillip; Goodman, Steven; Dhiantravan, Nattakorn; Esler, Rachel; Dunglison, Nigel; Navaratnam, Anojan; Yaxley, John; Thomas, Paul; Pattison, David A.; Goh, Jeffrey C.; Gan, Chun Loo; Roberts, Matthew J.
Source
European Journal of Nuclear Medicine and Molecular Imaging. 51(1):295-303
Subject
Language
English
ISSN
1619-7070
1619-7089
1619-7089
Abstract
Purpose: There is an emerging role of the use of Prostate-Specific Membrane Antigen (PSMA) Positron Emission Tomography (PET) in renal cell carcinoma. Herein, we report our experience in use of PSMA PET in recurrent or metastatic renal cell carcinoma (RCC).Methods: A retrospective analysis of all patients who underwent PSMA PET for suspected recurrent or de-novo metastatic RCC between 2015 and 2020 at three institutions was performed. The primary outcome was change in management (intensification or de-intensification) following PSMA PET scan. Secondary outcomes included histopathological correlation of PSMA avid sites, comparison of sites of disease on PSMA PET to diagnostic CT and time to systemic treatment.Results: