학술논문

Effect of Epithermal Neutrons on Viability of Glioblastoma Tumor Cells in Vitro
Document Type
Original Paper
Source
Bulletin of Experimental Biology and Medicine. June 2011 151(2):264-267
Subject
glioblastoma
proliferation
apoptosis
boron neutron capture therapy
cytofluorimetric analysis
Language
English
ISSN
0007-4888
1573-8221
Abstract
We studied in vitro effect of epithermal neutrons in various doses on viability of glioblastoma U87 tumor cells. Increasing the dose from 1.9 to 4.1 Sv promoted cell death. Cytofluorimetric analysis revealed no activation of apoptosis in the irradiated cells, which attested to necrotic death of the tumor cells exposed to epithermal neutron radiation.