부산대학교 도서관

Abstract.:Most reports of outcome following obesity surgery reportweight and co-morbidity changes only. We studied bodycomposition changes in 17 adult patients (15 F, 2 M, age 43±2years, range 28–58 years), with morbid obesity (initial BMI40.4±4.9 kg/m2, range 34.7–48.8) whowere managed surgically by laparoscopically inserting anadjustable gastric band. Body composition was studied before andafter surgery (mean interval of 909±51 days, range 441–1,155days) using anthropometry (abdominal circumference, AC, sum offour skinfold thicknesses, SFSUM), whole-body potassium counting(TBK), in vivo neutron activation analysis total body nitrogen(TBProtein) and whole-body dual-energy ray absorptiometry (totalbody percent fat TBF%, and total body bone mineral densityTBBMD). Weight loss over the study period was 23.4±2.5 kg.(p<0.0003) with an ACreduction of 20.0±4.5 cm (p<0.008). Both SFSUM and TBF% weresignificantly reduced (p<0.02 and p<0.0005 respectively). Both TBK andTBProtein after normalization for sex and height, weresignificantly (p<0.0054and p<0.001 respectively)reduced, but the ratio of loss of fat mass to fat-free mass, at4.4:1 was usual for weight loss, and there was no significantchanges in the ratio of potassium to protein. TBBMD, afternormalization relative to a young same sex adult, was notsignificantly changed. In this group of patients, most of thesubstantial weight loss over a 2- to 3-year period was due toloss of fat mass, with relatively less reduction in thecomponents of fat-free mass. Adjustable laparoscopic gastricbanding induces fat loss without significant other deleteriouseffects on body composition.