학술논문
Adverse effects of imidocarb dipropionate (Imizol® ) in a dog
Document Type
Original Paper
Source
Veterinary Research Communications: An International Journal Publishing Topical Reviews and Research Articles on all Aspects of the Veterinary Sciences. December 1984 8(1):55-59
Subject
Language
English
ISSN
0165-7380
1573-7446
1573-7446
Abstract
One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action.