부산대학교 도서관

Porous magnesium strontium phosphate (Sr3−xMgx(PO4)2) (x = 2, 2.5, 3) composite scaffolds were successfully prepared by three dimension gel-printing (3DGP) method in this study. The results show that Sr0.5Mg2.5(PO4)2 scaffolds had good compressive strength, and Sr1.0Mg2.0(PO4)2 scaffolds had good degradation rate in vitro. The weight loss rate of Sr1.0Mg2.0(PO4)2 scaffolds soaked in simulated body fluid (SBF) or 6 weeks was 6.96%, and pH value varied between 7.50 and 8.61, which was within the acceptable range of human body. Preliminary biological experiment shows that MC3T3-E1 cells had good adhesion and proliferation on the surface of Sr3−xMgx(PO4)2 scaffolds. Compared with pure Mg3(PO4)2 scaffolds, strontium doped scaffolds had excellent comprehensive properties, which explain that Sr3−xMgx(PO4)2 composite scaffolds can be used for bone tissue engineering.